Secondhand exposure to aerosol from electronic cigarettes: pilot study of assessment of tobacco-specific nitrosamine (NNAL) in urine |
| |
| Authors: | Jose M. Martínez-Sánchez Montse Ballbè Raúl Pérez-Ortuño Marcela Fu Xisca Sureda José A. Pascual Armando Peruga Esteve Fernández |
| |
| Affiliation: | 1. Group of Evaluation of Health Determinants and Health Policies, Universitat Internacional de Catalunya, Sant Cugat del Vallès (Barcelona), Spain;2. Tobacco Control Unit, Cancer Prevention and Control Program, Institut Català d’Oncologia, L’Hospitalet de Llobregat (Barcelona), Spain;3. Cancer Prevention and Control Group, Institut d’Investigació Biomèdica de Bellvitge - IDIBELL, L’Hospitalet de Llobregat (Barcelona), Spain;4. Catalan Network of Smoke-free Hospitals, L’Hospitalet de Llobregat (Barcelona), Spain;5. Addictions Unit, Institute of Neurosciences, Hospital Clínic de Barcelona, Barcelona, Spain;6. Department of Clinical Sciences, Universitat de Barcelona, Barcelona, Spain;7. Social and Cardiovascular Epidemiology Research Group, School of Medicine, University of Alcalá, Alcalá de Henares (Madrid), Spain;8. Hospital del Mar Medical Research Institute - IMIM, Barcelona, Spain;9. Department of Experimental and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain;10. Tobacco Free Initiatives, World Health Organization, Geneva, Switzerland |
| |
| Abstract: | ObjectiveTo assess the levels of a tobacco-specific nitrosamine (NNAL) in non-smokers passively exposed to the second-hand aerosol (SHA) emitted from users of electronic cigarettes (e-cigarettes).MethodWe conducted an observational study involving 55 non-smoking volunteers divided into three groups: 25 living at home with conventional smokers, 6 living with e-cigarette users, and 24 in control homes (smoke-free homes). We obtained urine samples from all volunteers to determine NNAL.ResultsWe detected NNAL in the urine of volunteers exposed to e-cigarettes (median:0.55 pg/mL; interquartile range: 0.26-2.94 pg/mL). The percentage of urine samples with quantifiable NNAL differed significantly among the three groups of homes: 29.2%, 66.7% and 76.0%, respectively (p = 0.004).ConclusionsWe found NNAL nitrosamine in urine samples from people exposed to SHA from e-cigarettes. However, these results could be confirmed with more studies with larger sample sizes. |
| |
| Keywords: | Corresponding author. Biomarkers Nitrosamines Second-hand aerosol Electronic cigarette Biomarcadores Nitrosaminas Aerosol de segunda mano Cigarrillo electrónico |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
