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Psoriatic skin molecular and histopathologic profiles after treatment with risankizumab versus ustekinumab
Authors:Sudha Visvanathan  Patrick Baum  Richard Vinisko  Ramona Schmid  Mary Flack  Bojan Lalovic  Oliver Kleiner  Judilyn Fuentes-Duculan  Sandra Garcet  Justin W. Davis  Kristie M. Grebe  Jay S. Fine  Steven J. Padula  James G. Krueger
Affiliation:1. Boehringer Ingelheim Pharmaceuticals, Ridgefield, Conn;2. Boehringer Ingelheim Pharma GmbH & Co KG, Biberach, Germany;3. Laboratory for Investigative Dermatology, Rockefeller University, New York, NY;4. AbbVie, North Chicago, Ill;5. AbbVie, Worcester, Mass;6. Boehringer Ingelheim Pharma GmbH & Co KG, Ingelheim, Germany
Abstract:
Keywords:Corresponding author: Sudha Visvanathan, PhD, Boehringer Ingelheim Pharmaceuticals, 900 Ridgebury Rd, Ridgefield, CT 06877.  Risankizumab  ustekinumab  IL-23  IL-12  IL-17  psoriasis  biomarkers  BLIMP-1  B lymphocyte-induced maturation protein-1  BSA  Body surface area  DC  Dendritic cell  DC-LAMP  Dendritic cell lysosome-associated membrane glycoprotein  DEG  Differentially expressed gene  FDR  False discovery rate  IL-17R  IL-17 receptor  LCN  Lipocalin  PASI  Psoriasis Area and Severity Index  RHE  Reconstructed human epidermal  RNA-seq  RNA sequencing
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