Killer immunoglobulin like receptor gene profiling in Western Indian population |
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Authors: | Selma Zenia D Silva,Sandeep Kumar Dhanda,Meenakshi Singh |
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Affiliation: | 1. HLA & Immunogenetics Laboratory, Department of Transfusion Medicine, Tata Memorial Hospital, Parel, Mumbai 400012, India;2. Division of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA 92037, USA |
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Abstract: | One hundred and sixty one healthy unrelated hematopoietic stem cell transplant donors from Western Indian were enrolled in this study. The study was initiated to observe the genotypic diversity of 16 killer immunoglobulin like receptor (KIR) genes in this population. KIR genotyping was carried out using the PCR-SSP technique. 56 KIR genotypes were observed in our population, where 15 genotypes were reported for the first time in any population. The KIR genotype data for the population can be accessed from Allele Frequencies Net Database under the population name “India Western KIR” and identifier “3570”. |
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Keywords: | Corresponding author. |
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