正常人全身骨量及人体组成变化(附292例DXA测量分析)

目的了解正常人全身骨量及人体组成变化,分析软组织成分与骨量的关系。方法选择292例正常人作为受检者,其中男性140人,女性152人;年龄10～79岁。采用双能X线骨密度仪测量全身骨矿含量(bonemineralcontent,BMC)、骨密度(bonemineraldensity,BMD)、肌组织(lean)和脂肪组织(fat)。按10岁为1个年龄组对各组数据进行统计分析。结果男性BMC、BMD、lean、fat峰值分别出现在30～39岁、20～39岁、30～39岁、70～79岁年龄组;女性则分别出现在30～39岁、30～39岁、30～49岁、50～69岁年龄组。男性BMC、BMD、lean峰值高于女性,但BMD差异无显著性(P>0.05)。女性fat峰值高于男性。女性BMC、BMD峰值后下降幅度较男性显著,男性lean峰值后下降幅度较女性显著。男性骨量与lean和体重(weight)呈高、中度相关(P<0.01),女性骨量除与lean、weight呈高、中度相关外(P<0.01),fat与BMC的相关系数r值较男性稍高。结论提供了正常人各年龄组全身骨量及人体组成的正常数据和变化特点,初步探讨了骨量与软组织成分之间的关系。

Bone mineral and body composition analysis of whole body in 292 normal subjects assessed by dual X-ray absorptiometry

OBJECTIVE: To understand whole body bone mineral and body composition changes in normal subjects, and study the relationship between body composition and bone mineral. METHODS: 292 normal subjects aged 10-79 years old, including 140 males and 152 females, were selected to be measured bone mineral content (BMC), bone mineral density (BMD) lean and fat of whole body by dual X-ray absorptiometry (DXA). Individuals were divided into age-groups by every ten years and were analyzed by statistical methods. RESULTS: In males, peak values of BMC, BMD, lean and fat were in the 30-39, 20-39, 30-39, 70-79 age-groups. In females, they were in the 30-39, 30-39, 30-49, 50-69 age-groups respectively. Peak values of BMC, BMD and lean were higher in males than that in females, but peak value of BMD was not significantly higher in males than that in females. Peak value of fat was higher in females than that in males. Loss of BMC and BMD for females were more pronounced than that for males. Loss of lean for males was more pronounced than that for females. There are significant positive correlation between lean, weight and bone mineral in males and females. Fat has significant effect on BMC in females only. CONCLUSIONS: The normal bone mineral and body composition data of whole body for males and females, and the characteristic of changes with aging are provided for analyzing the relationship between bone mineral and body composition with ease.