椎弓根螺钉固定联合椎体成形术治疗老年胸腰段骨折的初步疗效观察

目的 探究椎体成形术联合椎弓根螺钉内固定对脊柱胸腰段骨折患者功能恢复的影响.方法 前瞻性收集安徽中医药大学附属太和县中医医院2016年1月至2018年12月收治的脊柱胸腰段骨折患者96例,使用随机数字表法将其分为单一组(48例)及联合组(48例),单一组使用椎弓根螺钉内固定术进行治疗,联合组在其基础上加用椎体成形术.观...

Effect of vertebroplasty combined with pedicle screw internal fixation on functional recovery of patients with thoracolumbar fractures of the spine

Objective To investigate the effect of vertebroplasty combined with pedicle screw fixation on functional recovery in patients with thoracolumbar fracture.Methods A total of 96 patients with thoracolumbar spine fractures admitted to our hospital from January 2016 to December 2018 were selected and randomly divided into a single group(48 cases)and a combined group(48 cases).The single group was treated with pedicle screw fixation,while the combined group was treated with vertebra plasty.The recovery,pain and dysfunction indexes of the injured vertebrae in the two groups before and after surgery were observed and compared.The indexes related to serum nerve function in the two groups before and after surgery were detected and compared,and the incidence of postoperative adverse events in the two groups were recorded.Results Three days after surgery,there was no significant difference in the recovery of injured vertebrae between the two groups(P>0.05).On postoperative 3 d,there was no significant difference in Visual Analogue Scale/Score(VAS)and Oswestry Dability Index(ODI)scores between the two groups(P>0.05).Three months after surgery,VAS and ODI scores of the combined group were significantly lower than those of the single group(P<0.05).On postoperative day 3,there was no significant difference in the levels of neuron specific enolase(NSE),brain derived neurotrophic factor(BDNF),S100 and Nerve growth factor(NGF)between the two groups(P>0.05).NSE,S100 beta and NGF levels were significantly lower in the single group(P<0.05).The incidence of adverse events in the combined group was significantly lower than that in the single group(P<0.05).Conclusion vertebroplasty combined with pedicle screw internal fixation to thoracolumbar fracture of spine can effectively improve the recovery of vertebral body after surgery,reduce postoperative pain and dysfunction,improve postoperative neurological function,and reduce the incidence of adverse events.