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干扰素联合微卡治疗慢性乙型肝炎
引用本文:尹华,陈启红,沈莉华,林帆. 干扰素联合微卡治疗慢性乙型肝炎[J]. 中国综合临床, 2005, 21(9): 798-799
作者姓名:尹华  陈启红  沈莉华  林帆
作者单位:1. 512028,广东省韶关市粤北第二人民医院传染科
2. 广州市第一人民医院肝胆外科
摘    要:目的 探讨干扰素联合微卡治疗慢性乙型肝炎的作用机制及疗效。方法 按诊断标准选择慢性乙型肝炎患者80例,随机分为干扰素联合微卡治疗组(40例)和干扰素对照组(40例),观察比较两组患者肝功能、HBeAg及HBV-DNA的变化。结果 治疗组的肝功能复常率、HBeAg及HBV-DNA阴转率均明显高于对照组(P〈0.05)。结论 干扰素联合微卡治疗慢性乙型肝炎有协同作用,促进HBeAg及HBV-DNA的阴转。

关 键 词:乙型肝炎  干扰素  微卡  治疗
文章编号:1008-6315(2005)09-0798-02
修稿时间:2005-03-08

Interferon combined with M.vaccae in treatment of chronic hepatitis B
Abstract:Objective To study the mechanism and effect of interferon combined with M.vaccae in the treatment of chronic hepatitis B.Methods 80 cases of chronic hepatitis B were randomly divided into interferon combined with M.vaccae treatment group (n=40) and interferon control group (n=40).Liver function,HbeAg and HBV DNA were compared between groups.Results The recovery rate of liver function,the negative rates of HbeAg and HBV DNA were significantly higher in treatment group than those in control group (P<0.05).Conclusion Interferon combined with M.vaccae has a cooperative effect in the treatment of chronic hepatitis B,and it is apt to improve the negative rates of HbeAg and HBV DNA.
Keywords:Hepatitis B  Interferon  M.Vaccae
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