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| 体感诱发电位对大面积脑梗死纳洛酮疗效的动态研究 | |
| 引用本文： | 童绥君,蔡小芳,黄琼华,林青山. 体感诱发电位对大面积脑梗死纳洛酮疗效的动态研究[J]. 中华急诊医学杂志, 2001, 10(1): 28-29 |
| 作者姓名： | 童绥君 蔡小芳 黄琼华 林青山 |
| 作者单位： | 福建省厦门市中山医院神经内科 |
| 基金项目： | 福建省卫生厅科研基金! ( 96 0 0 81) |
| 摘 要： | 目的 将脑梗死纳 络酮即刻效应与体感诱发电位（SEP） 脑功能评价法相结合，以探讨脑梗死的神经功能变化和纳洛酮对其的影响。方法 结合临床和影像资料，动态分析纳洛酮治疗脑梗死前后的SEP表现。结果 皮层电位N20未引出的责任病灶，一是丘脑梗死，二是放射冠和顶叶梗死；N20再现与纳洛酮药效相一致；纳洛酮对脑梗死的影响，与改善神经传导功能相比，主要是提高大脑神经元兴奋性。结论 SEP即是评价脑梗死纳洛酮即刻疗效的客观、敏感方法，又可用于探讨纳酮作用机制。 |
| 关 键 词： | 脑梗死 纳洛酮 体感诱发电位 SEP |
| 修稿时间： | 2000-09-13 |
A dynamic study using SEP of the therapeutic effect of naloxone on cerebral infarct |
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| TONG Suijun,CAI Xiaofang,HUANG Qionghua,et al.. A dynamic study using SEP of the therapeutic effect of naloxone on cerebral infarct[J]. Chinese Journal of Emergency Medicine, 2001, 10(1): 28-29 | |
| Authors: | TONG Suijun CAI Xiaofang HUANG Qionghua et al. |
| Affiliation: | TONG Suijun,CAI Xiaofang,HUANG Qionghua,et al.Department of Neurology,Xiamen Zhongshan Hospital,Fujian 361004 |
| Abstract: | Objective To explore the neural function change in cerebral infarct and the effect of naloxone as well as the immediate effect of naloxone on brain function as evaluated by SEP（somatosensory evoked potential）．Methods With a comprehensive study of clinical & imaging data，we analysed dynamically the brain infarction SEP before & after naloxone treatment．Results The responsible foci not elicited by cortical potential N20are thalamus infarction，and coronal radiation & parietal lobe infarction．The N20 recurrence is consistent with naloxones therapeutic effect．The effect of naloxone is mainly to increase neuronal excitability，while at the same time，to ameliorate nervous conductivity．Conclusion SEP can be an objective & sensitive method of evaluating naloxones instant effect on cerebral infarction，and can be used to explore the functional mechanism of naloxone． |
| Keywords: | Cerebral infarct Naloxone Somatosensory evoked potential |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |