| 系统性硬化病患者的食物胃排空和胃内分布 |
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| 引用本文： | 莫剑忠 王承党. 系统性硬化病患者的食物胃排空和胃内分布[J]. 中华内科杂志, 1996, 35(8): 530-532 |
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| 作者姓名： | 莫剑忠 王承党 |
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| 作者单位： | 上海第二医科大学附属仁济医院 |
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| 摘 要： | 为探讨无消化道症状的系统性硬化病（ＳＳ）患者的胃排空功能，以双核素标记试餐及单光子发射计算机断层摄影（ＳＰＥＣＴ）技术检测了１１例无消化道症状的ＳＳ患者之液体与固体食物的胃排空和胃内分布，对照组为１７例健康志愿者。结果：ＳＳ组液体和固体食物的近端胃排空和全胃排空均慢于对照组（Ｐ值＜０．０５）；液体和固体食物的近端胃半排空时间均与它们的全胃半排空时间之间存在正相关（Ｐ值分别＜０．０２和０．０１）。９例患者固体半排空时间延迟，其中８例伴液体排空障碍。在食物的排空过程中，远端胃内的活性变化与对照组的差异无显著性。结果提示：尽管缺乏胃轻瘫的主观症状，但该组患者也存在明显的胃排空障碍，这可能与其神经功能紊乱所致的近端胃的紧张性收缩障碍有关。
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| 关 键 词： | 硬皮病.系统性 胃排空 |
GASTRICEMPTYINGANDINTRAGASTRICDISTRIBUTIONOFLIQUIDANDSOLIDMEALINPATIENTSWITHSYSTEMICSCLEROSISMo |
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| Jianzhong,WangChengdang,WangShaoxian,et al.. GASTRICEMPTYINGANDINTRAGASTRICDISTRIBUTIONOFLIQUIDANDSOLIDMEALINPATIENTSWITHSYSTEMICSCLEROSISMo[J]. Chinese journal of internal medicine, 1996, 35(8): 530-532 |
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| Authors: | Jianzhong WangChengdang WangShaoxian et al. |
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| Affiliation: | Jianzhong,WangChengdang,WangShaoxian,etal.RenjiHospitalAffiliatedtoShanghaiSecondMedicalUniversity,Shanghai200001 |
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| Abstract: | Toevaluatethegastricemptyingfunctionsinpatientswithsystemicsclerosis(SS),gas-tricemptyingandintragastricdistributionduringemptyingafteraliquid-solidmealwerestudiedbysin-glephotonemissioncomputedtomographyin11patientswithoutgutsymptomsandin17healthyvolun-teers.Inpatientgroup,halfemptyingtimesbothofproximal(pT50)andoftotalstomach(T50)forbothmealcomponentsweresignificantlylongerthanincontrols.ThereweresignificantrelationshipsrespectivelybetweentheT50andthepT50forbothliquidandsolidmeal.Outof11cases,9haddelayedT50ofsolid,whichwereaccompaniedbydelayedemptyingofliquidin8patients.Theprolongationofgastricemptyingofsolidcorrelatedsignificantlywiththedurationofthedisease.However,thechangesoftheactivity-timecurvesinthedistalstomachduringemptyingwerenotreachingsignificantlevelwhencomparedtothecontrols.InconclusiondespitenoexistenceofanygutsymptomsourSSpatientspresentsignificantdelayedgastricemptying,whichmaybecorrelatedtothedysfunctionoftoniccon-tractionoftheproximalstomachatributedtoautonomicneuropathy. |
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| Keywords: | Scleroderma systemicGastricemptying |
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