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颅内动脉瘤患者主动脉弹性功能变化及临床意义
引用本文:Pu ZX,You XD,Weng WC,Wang JA,Shi J. 颅内动脉瘤患者主动脉弹性功能变化及临床意义[J]. 浙江大学学报(医学版), 2011, 40(5): 550-554. DOI: 10.3785/j.issn.1008-9292.2011.05.015
作者姓名:Pu ZX  You XD  Weng WC  Wang JA  Shi J
作者单位:浙江大学医学院附属第二医院,浙江杭州,310009
摘    要:
目的:观测颅内动脉瘤患者的主动脉弹性功能,探讨其功能变化的临床意义.方法:选择107例颅内动脉瘤患者(其中伴发高血压者57例)和108例正常对照者,M型超声心动图测量升主动脉收缩期(AoS)及舒张期(AoD)内径,计算并比较各组主动脉弹性功能指标.结果:①与正常对照组比较:颅内动脉瘤高血压组、非高血压组患者的主动脉膨胀性( aortic distensibility,DIS)均明显降低(P<0.001),而僵硬度(aortic stiffness index,SI)明显增加(P <0.001).②与颅内动脉瘤非高血压组比较,伴有高血压的颅内动脉瘤患者DIS明显降低(P<0.001),而SI有所升高(P<0.05).三组间经体表面积、体重指数校正后的校正值亦存在同样规律.结论:颅内动脉瘤患者均存在主动脉弹性功能的减退,且高血压是引起该疾患主动脉弹性功能进一步减退的原因之一.

关 键 词:颅内动脉瘤/超声检查  超声心动描记术  弹性  主动脉  高血压

Aortic elastic properties and its clinical significance in intracranial aneurysms
Pu Zhao-xia,You Xiang-dong,Weng Wen-chao,Wang Jian-an,Shi Jian. Aortic elastic properties and its clinical significance in intracranial aneurysms[J]. Journal of Zhejiang University. Medical sciences, 2011, 40(5): 550-554. DOI: 10.3785/j.issn.1008-9292.2011.05.015
Authors:Pu Zhao-xia  You Xiang-dong  Weng Wen-chao  Wang Jian-an  Shi Jian
Affiliation:PU Zhao-xia,YOU Xiang-dong,WENG Wen-cao,WANG Jian-an,SHI Jian(The Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310009,China)
Abstract:
Objective: To investigate the aortic elastic properties and its clinical significance in intracranial aneurysms(IAs). Methods: One hundred and seven IAs patients(57 with hypertension) and 108 healthy subjects were recruited.The internal aortic diameters in systole and diastole were measured by the M-mode echocardiography,the aortic elasticity indexes were calculated and compared. Results: The aortic distensibility(DIS) was lower and the aortic stiffness index(SI) was higher in IAs patients than those in con...
Keywords:Intracranial aneurysm/ultrasonogr  Echocardiography  Elasticity  Aorta  Hypertension  
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