| 核桃楸树皮乙酸乙酯提取物对原位移植荷胃癌小鼠的抑瘤作用 |
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| 引用本文： | 林瑞新,杨淑莉,房学东,宫路路,张研.核桃楸树皮乙酸乙酯提取物对原位移植荷胃癌小鼠的抑瘤作用[J].吉林大学学报(医学版),2011,37(2):260-263. |
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| 作者姓名： | 林瑞新 杨淑莉 房学东 宫路路 张研 |
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| 作者单位： | 吉林大学第二医院普通外科,吉林,长春,130041;吉林大学第二医院妇产科,吉林,长春,130041 |
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| 基金项目： | 吉林省科技厅科技发展计划项目资助课题 |
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| 摘 要： | 目的:研究核桃楸树皮乙酸乙酯提取物(HYT)对原位移植荷胃癌小鼠的抑瘤作用及其对免疫功能的影响,阐明HYT抗胃癌作用机理,为研发低毒高效的抗胃癌中草药提供理论依据.方法:建立HYT灌胃的原位移植荷胃癌小鼠研究模型,分为HYF高剂量组(60 mg·kg-1)、HYF低剂量组(40 mg·kg-1)、假手术组、阳性对照组(...
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| 关 键 词： | 桃楸树皮乙酸乙酯提取物 抗肿瘤活性 胃肿瘤 原位移植 |
| 收稿时间： | 2010-09-11 |
Anti-tumor effect of extract from Bark of Juglans Mandshurica Maxim on gastric cancer mice in vivo |
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| LIN Rui-xin,YANG Shu-li,FANG Xue-dong,GONG Lu-lu,ZHANG Yan.Anti-tumor effect of extract from Bark of Juglans Mandshurica Maxim on gastric cancer mice in vivo[J].Journal of Jilin University: Med Ed,2011,37(2):260-263. |
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| Authors: | LIN Rui-xin YANG Shu-li FANG Xue-dong GONG Lu-lu ZHANG Yan |
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| Institution: | (1.Department of General Surgery |Second Hospital,Jilin University,Changchun130041,China；
2. Department of Gynecology and Obotetrics|Second Hospital,Jilin University,Changchun 130041,China) |
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| Abstract: | Objective To study the anti-tumor activity and effect on immune function of extract from Bark of Juglans Mandshurica Maxim(HYT)in orthotopic transplantation of gastric cancer mice and illustrate its underlying mechanism and provide theoretical basis for developing traditional low-toxicity and high-performance anti-tumor Chinese medicine and herbs in clinic.Methods The orthotopic transplantation of gastric cancer mouse models were established with HYT.The mice were divided into high dose of HYT group,lower d... |
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| Keywords: | extract from Bark of Juglans Mandshurica Maxim anti-tumor activity stomach neoplasms orthotopic transplantation |
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