胃肠黏膜相关淋巴组织淋巴瘤43例临床分析

【目的】总结胃肠黏膜相关淋巴组织（MALT）淋巴瘤的诊治体会及经验。【方法】对200l~2008年收治的43例胃肠MALT淋巴瘤患者进行回顾性分析。【结果】①胃肠MALT淋巴瘤多发生于50岁以上者，男性多于女性；②胃肠MALT淋巴瘤内镜下表现多样化、无特异性，镜检时应采取多点活检、免疫组化标记以提高早期检出率；③治疗以化疗为主，巨大胃溃疡或肠MALT淋巴瘤加以手术切除，以改善其生活质量，延长生存期。【结论】胃肠MALT淋巴瘤临床表现不典型，确诊应根据内镜、病理和免疫组化结果综合判断。

Clinical Analysis of 43 Cases of Gastrointestinal Mucosa-associated Lymphoid Tissue Lymphoma

[Objective]To summarize the experiences of the diagnosis and treatment of gastrointestinal mu- cosa-associated lymphoid tissue（MALT） lymphoma. [Methods] The clinical data of 43 cases of MALT lymphoma treated in our hospital from 2001 to 2008 were retrospectively analyzed. [Results] Most of the patients were more than 50 years old, and the number of male patients were more than that of female patients. Under endoscopy, the manifestation of MALT lymphoma was varied and had no specificity, and multipoint biopsy and immunohistochemical label should be used to increase the early detection rate. The major treatment was chemotherapy. Great MALT lymphoma should be additionally removed by operation in order to improve the quality of life and prolong the life cycle. [Conclusion]The clinical manifestation of gastrointestinal MALT lymphoma is not typical, so it should be judged by endoscopy, pathology and immunohistochemistry.