| 活血化瘀重剂治疗早期糖尿病肾病的疗效与机制探讨 |
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| 引用本文： | 王小超,刘克冕,狄红杰,冯栋年.活血化瘀重剂治疗早期糖尿病肾病的疗效与机制探讨[J].光明中医,2009,24(11):2060-2062. |
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| 作者姓名： | 王小超 刘克冕 狄红杰 冯栋年 |
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| 作者单位： | 江苏省中西医结合医院内分泌科,南京,210028 |
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| 摘 要： | 目的：观察破血逐瘀、益气养阴方治疗早期糖尿病肾病（DN）患者的疗效。方法：将96例早期DN患者随机分为2组,对照组46例使用西药口服降糖药或（和）胰岛素控制血糖;治疗组50例在此基础上使用中药破血化瘀、益气养阴方,每日1剂,1月为1疗程,共观察2个疗程。结果：治疗组治疗前后症状积分比较、治疗组与对照组治疗前后症状改善值比较,有统计学差异（P〈0.05）。治疗组治疗前后、治疗组与对照组UAER改善值比较均有统计学差异（P〈0.05）。血液流变学参数在治疗组治疗前后比较、治疗组与对照组症状改善值d比较,差异具统计学意义（P〈0.05）。在调节血糖（TC、TG、HDL-C）方面,治疗组治疗前后、治疗组与对照组改善值比较差异有统计学意义（P〈0.05）。结论：本方治疗早期DN获得疗效。
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| 关 键 词： | 活血化瘀 糖尿病肾病 肌酐清除率 血脂 血液流变 |
Effect of Huoxuehuayu ZhongJi in Diabetic Nephropathy |
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| Wang Xiaochao,Liu Kemian,Di Hongjie,Feng Dongnian.Effect of Huoxuehuayu ZhongJi in Diabetic Nephropathy[J].Journal of Traditional Chinese Medicine,2009,24(11):2060-2062. |
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| Authors: | Wang Xiaochao Liu Kemian Di Hongjie Feng Dongnian |
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| Institution: | Wang Xiaochao Liu Kemian Di Hongjie Feng Dongnian |
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| Abstract: | Objective:To study the effects of Huoxuehuayu Zhong Ji on patients with early diabetic nephropathy(DN).Methods:96 type 2 DN patients were randomly divided into the treated group(n=50)and the control group(n 46).All patients were treated with conventional hypoglycemic agents and hypotensor,but those in the treated group were given additionally with Huoxuehuayu Zhong Ji twice a day for 2 months.The changes of urinary albumin excretion rate (UAER),hemoreheologic parameters and blood lipids,including total chol... |
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| Keywords: | Huoxuehuayu Zhong Ji diabetic nephropathy urinary albumin excretion rate hemoreheologic parameters blood lipids |
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