Emesis in patients receiving acupuncture,sham acupuncture or standard care during chemo-radiation: A randomized controlled study |
| |
| Institution: | 1. The Social Rehabilitation Unit, Sundsvall Municipality and Department of Medical and Health Sciences, Division of Physiotherapy, Linköping University, Linköping, Sweden;2. Region of Östergötland, Department of Medical and Health Sciences, Division of Physiotherapy, Linköping University, Linköping, Sweden;1. Escola de Terapias Orientais de São Paulo-(ETOSP/SP), Brazil;2. Universidade Cruzeiro do Sul, São Paulo, Brazil;3. Motilidade Digestiva e Neurogastroenterologia – (MoDiNe), São Paulo, Brazil;1. School of Persian and Complementary Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;2. Department of Pharmaceutical Sciences in Persian Medicine, School of Persian and Complementary Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;3. Department of Community Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;4. Department of Persian Medicine, School of Persian and Complementary Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;5. Department of Gynecology and Obstetrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;6. Department of Chinese and Complementary Medicine, School of Persian and Complementary Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;1. School of Nursing, College of Nursing, National Taipei University of Nursing and Health Sciences, No. 365 Min-Te Road, Taipei 11219, Taiwan, ROC;2. Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taiwan, ROC;3. Division of General Surgery, Department of Surgery, Taipei Medical University—Shuang Ho Hospital, No. 250, Wu-Hsing Street., Wu-Hsing District, Taipei 11031, Taiwan, ROC;4. Graduate Institute of Integration of Traditional Chinese Medicine with Western Nursing, College of Nursing, National Taipei University of Nursing & Health Sciences, No. 365, Min-Te Road, Taipei 11219, Taiwan, ROC;1. The Hong Kong Polytechnic University, School of Nursing, Hung Hom, Kowloon, Hong Kong Special Administrative Region;2. Charles Darwin University, College of Nursing and Midwifery Brisbane Centre, Level 11, 410 Ann Street, Brisbane, QLD, 4000, Australia;3. Fujian Provincial Cancer Hospital, Department of Breast Oncology, Fuma Road, Jinan District, Fuzhou, Fujian, 340014, China;1. Charles Darwin University, Faculty of Health, Brisbane Centre, 410 Ann Street, Brisbane, QLD, Australia;2. Charles Darwin University, Faculty of Health, Ellengowan Drive, Darwin, NT, Australia;3. The Hong Kong Polytechnic University, School of Nursing, Hung Hom, Kowloon, Hong Kong Special Administrative Region;4. Queensland University of Technology, Cancer & Palliative Outcomes Centre, Kelvin Grove, QLD, Australia;5. Thornlands General Practice, Thornlands, Redland, QLD, Australia |
| |
| Abstract: | ObjectiveTo study nausea, vomiting and need for rescue antiemetics in patients receiving antiemetic acupuncture, sham acupuncture or standard care during concomitant chemotherapy during pelvic radiotherapy.MethodsIn total, 68 patients participated (75% women, mean age 56 years, 53% had gynecological, 43% colorectal, and 4% other cancer types). Fifty-seven of them were blinded randomized to verum (n = 28) or sham (n = 29) acupuncture, median 10 sessions. During the study period of four weeks, the patients daily registered their nausea, vomiting and consumption of antiemetics. They were compared to a reference group (n = 11) receiving standard care only, who delivered these data once (after receiving mean 27 Gy radiotherapy dose).ResultsMore patients in the sham acupuncture group (17 of 20; 85%, p = 0.019, RR 1.81, CI 1.06–3.09) consumed antiemetics, compared to the verum acupuncture group (8 of 17; 47%). In the standard care group, 7 of 11 (63%) consumed antiemetics. The verum acupuncture treated patients experienced lower intensity of nausea than the other patients (p = 0.049). There was a non-significant tendency that more patients receiving either sham acupuncture or standard care experienced nausea (21 of 31; 68%) than patients receiving verum acupuncture (9 of 17; 53%: p = 0.074, RR 1.58, CI 0.91–2.74).ConclusionPatients treated with verum acupuncture needed less antiemetics and experienced milder nausea than other patients. Our study was small and many analyses lacked statistical power to detect differences; we welcome further sham-controlled efficacy studies and studies regarding the role of non-specific treatment components for experiencing antiemetic effects of acupuncture. |
| |
| Keywords: | Acupuncture therapy Complementary and alternative medicine Nausea Supportive care Vomiting |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
