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Topical garlic treatment for verruca plana triggers Koebner phenomenon: A case report
Authors:Tianhang Yu MD  Jiaozi Che MD  Jikai Song MD  Xinsuo Duan MD  Jie Yang MD  PhD
Affiliation:1. Department of Dermatology, Affiliated Hospital of North China University of Science and Technology, Tangshan, Hebei Province, China;2. Department of Clinical Laboratory, Chengde Central Hospital, Chengde, Hebei Province, China;3. Zhejiang Provincial People's Hospital, Qingdao University, Hangzhou, Zhejiang Province, China;4. Department of Dermatology, Affiliated Hospital of Chengde Medical College, Chengde, Hebei Province, China
Abstract:

Background

Verruca plana is a benign proliferation of the skin caused by human papilloma virus (HPV) infection. Fresh garlic can serve as an alternative therapy, and it has shown considerable effectiveness as a topical treatment for verruca plana. However, topical garlic treatment for verruca plana triggered Koebner phenomenon (KP), which has not been previously reported.

Aim

The aim of our report is to explore the possible causes of this adverse reaction.

Method

We here describe a 20-year-old female patient who developed a beaded rash after garlic treatment for facial wart plana, known as autoinoculation or KP.

Results

Garlic may have caused damage to the surrounding normal skin through primary irritation or allergic reactions. Then, the HPV virus on the primary verruca plana took the opportunity to spread to the surrounding skin injured by garlic stimulation, triggering the KP.

Conclusion

When using garlic to treat verruca plana, the operator needs to precisely apply the mashed garlic to the warts, and this treatment is strictly prohibited for patients who are allergic to garlic. Avoid such adverse reactions.
Keywords:autoinoculation  garlic  pseudo-koebnerization  verruca plana
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