突触的可塑性研究──大鼠运动神经末梢增龄变化

目的探讨大鼠运动神经末梢随年龄变化的规律，为同类研究提供正常参考。方法借助组化方法显示运动神经末梢、肌纤维、运动终板及其发芽，并行定量研究。结果大鼠比目鱼肌运动神经末梢一生都在进行着终板发芽，年轻至老年前期较为明显，老年时减弱。结论年轻大鼠随年龄增长，运动神经末梢分枝点增多，终板增大，到了老年，终权简单化。

Study of synaptic plasticity changes of motor nerve endings in rats with increasing age

Objective To study the regularity of motor nerve ending sproutings in rats with increasing age.Method The motor nerve endings, muscular fibers and motor nerve endplate in rat are demonstrated simultaneously with histochemistry method, and are investigated quantitatively.Result Endplate length was increased with increasing age. Branch points of the motor nerve ending in soleus muscles of rats was increased with ageing from 1. 5 mo-15. 5 mo in rats. But in senile, branch points were deminished.Conclusion Motor nerve endings in rats undergo terminal sprouting in life which is obvious in young rat, but is decreased in senil rat.