老年原发性高血压患者脑导纳指标改变的特点及临床意义

目的　研究老年原发性高血压患者双侧脑血流导纳指标改变及其临床意义。方法　对 6 6例确诊为老年原发性高血压患者行双侧脑血流检测 ,分析脑导纳各项指标的特点 ,并与 5 0例健康老年人作对照。结果　老年原发性高血压患者的脑导纳改变 ,与健康对照组相应指标比较 :表现为流入容积速度 [波幅 (HS) 快速充盈时间 (BS) ]比值显著降低 (P <0 .0 1) ,流入阻力指数 [转折高 (HH) 波幅 (HS) ]比值显著降低 (P <0 .0 0 1) ,Ⅰ +Ⅱ相面积百分比显著降低 (P <0 .0 0 1) ,Ⅳ相面积百分比显著增高 (P <0 .0 0 1) ,导纳微分环 (ADL)Ⅳ ADLⅠ +Ⅱ显著增高 (P <0 .0 0 1) ,二次谐波 基波、三次谐波 基波、四次谐波 基波、五次谐波 基波、六次谐波 基波、七次谐波 基波、十次谐波 基波比值均显著增高 (P <0 .0 1～P <0 .0 0 1) ,Ⅰ相缺蚀评价分值增大 (P <0 .0 0 1)。结论　老年原发性高血压患者双侧脑血流导纳检测呈明显特征性改变 ,该结果可提供评价老年原发性高血压患者脑血管及脑供血状态的客观指标。

Characteristics and clinical significance of changes in cerebral electrical admittance plethysmogram of senile patients with essential hypertension

Objective To study the changes and clinical significance of bilateral cerebral electrical admittance plethysmogram in senile patients with essential hypertension.Method Bilateral cerebral electrical admittance was measured in 66 senile patients who had been diagnosed as essential hypertension.The features of its various indexes were analyzed and compared with those in 50 normal senile people.Results Compared with the normal group,the changes in cerebral electrical admittance plethysmogram of the group of patients indicated that the ratio of HS to BS(HS/BS) increased significantly (P<0.01); the ratio of HH to HS (HH/HS)decreased significantly(P<0.001),the percentage of the phase Ⅰ+Ⅱ area decreased significantly(P<0.001);the index of Admittance Differential Loop (ADL) Ⅰ+Ⅱ decreased significantly(P<0.001); the percentage of the phase Ⅳ area increased significantly(P<0.001);the ADLⅣ/ADL Ⅰ+Ⅱ increased significantly (P<0.01-P<0.001);the respective ratios of the second,the third,the fourth,the fifth,the sixth,the seventh and the tenth resonant wavelength to basic wavelength increasd significantly(P<0.01-P<0.001);phase Ⅰ area flaw mark increased significantly(P<0.001).Conclusions Bilateral cerebral electrical admittance plethysmogram of the group of essential hypertensive patients showed remarkable characteristic changes.This examination method provides objective index for judging the state of cerebral blood fluid in essential hypertensive patients.