| 腹腔镜联合人工授精治疗子宫内膜异位症不孕的临床观察 |
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| 引用本文： | 蒋亚玲,邢福祺,李冰,全松,冯健怀. 腹腔镜联合人工授精治疗子宫内膜异位症不孕的临床观察[J]. 热带医学杂志, 2011, 11(5): 583-586 |
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| 作者姓名： | 蒋亚玲 邢福祺 李冰 全松 冯健怀 |
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| 作者单位： | 1. 南方医科大学南方医院生殖医学中心,广东,广州,510515
2. 广州医学院第三附属医院妇产科,广东,广州,510150 |
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| 基金项目： | 广东省自然科学基金(5002464) |
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| 摘 要： | 目的探讨子宫内膜异位症(EMs)不孕患者腹腔镜术后行夫精人工授精妊娠率的影响因素。方法回顾性分析164例腹腔镜术后的EMs不孕患者进行的318个人工授精周期的临床资料。以年龄、不孕年限、腹腔镜术后时间、用药情况、周期数、是否促排卵、r-AFS分期、IUI时机分别进行妊娠率的比较。结果 EMs不孕患者术后人工授精的周期妊娠率为13.21%。年龄≤35岁的周期妊娠率高于35岁以上者(χ2=6.687,P<0.05),不孕年限≤5年的妊娠率高于5年以上者(χ2=5.430,P<0.05),腹腔镜术后1年内行人工授精的妊娠率高于1年以上者(χ2=6.005,P<0.05),Ⅰ～Ⅱ期患者的妊娠率高于Ⅲ～Ⅳ期患者(χ2=8.264,P<0.05),加用促排卵治疗的妊娠率高于自然周期者(χ2=4.569,P<0.05),3周期内人工授精的妊娠率高于3周期以上者(χ2=4.031,P<0.05),双次IUI者妊娠率高于单次者(χ2=4.371,P<0.05),差异均有统计学意义。而术后是否使用GnRH-a则与妊娠率无关。结论 EMs不孕患者腹腔镜术后行人工授精治疗的最佳时间是术后1年内3周期内有较高的妊娠率,建议同时加用促排卵治疗。
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| 关 键 词： | 子宫内膜异位症 不孕症 宫腔内人工授精 |
Clinic study on laparoscopic operation combined with intrauterine insemination treatment for endometriosis-associated infertility |
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| JIANG Ya-ling,XING Fu-qi,LI Bing,QUAN Song,FENG Jian-huai. Clinic study on laparoscopic operation combined with intrauterine insemination treatment for endometriosis-associated infertility[J]. Journal Of Tropical Medicine, 2011, 11(5): 583-586 |
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| Authors: | JIANG Ya-ling XING Fu-qi LI Bing QUAN Song FENG Jian-huai |
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| Affiliation: | JIANG Ya-ling1,XING Fu-qi1,LI Bing2,QUAN Song1,FENG Jian-huai2(1.Center for Reproductive Medicine,Nanfang Hospital,Southern Medical University,Guangzhou 510515,2.Department of Obstetrics and Gynecology,the Third Affiliated Hospital of Guangzhou Medical College,Guangzhou 510150,China) |
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| Abstract: | Objective To investigate factors affecting pregnancy rate of artificial insemination for endometriosis-associated infertile patients after laparoscopic operation.Methods 164 endometriosis-associated infertile patients after laparoscopic operation have received 318 cycles of intrauterine insemination(IUI).Comparison of pregnancy rate are conducted on age,infertile time,controlled ovary hyperstimulation(COH),r-AFS staging,medication,time and cycle number after operation and IUI frequency.Results Cycle pregnan... |
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| Keywords: | endometriosis infertility intrauterine insemination |
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