红细胞分布宽度对老年急性肺栓塞患者近期预后的影响分析

目的探讨红细胞分布宽度(RDW)对老年急性肺栓塞患者近期预后的影响。方法回顾性分析我院81例老年急性肺栓塞患者临床资料,根据RDW水平分为3组,RDW低值组27例,RDW中值组27例,RDW高值组27例,比较3组患者住院死亡、休克发生率及其他血流动力学、实验室指标。结果随RDW水平升高,RDW低值组、RDW中值组和RDW高值组住院病死率、死亡和休克总发生率、N末端B型利钠肽前体水平明显增加(P<0.05)。Pearson相关分析显示,与死亡发生的相关因素是年龄、收缩压、心率、N末端B型利钠肽前体、肌钙蛋白I、RDW(P<0.05,P<0.01)。logistic多因素回归分析显示,年龄、收缩压、心率是住院死亡的独立影响因素(P<0.05,P<0.01)。结论老年急性肺栓塞患者RDW升高者住院死亡和休克的发生率增加。

Effect of red cell distribution width on early prognosis of elderly acute pulmonary embolism patients

Objective To study the effect of red cell distribution width on early prognosis of elderly acute pulmonary embolism patients.Methods Clinical data about 81 elderly acute pulmonary embolism patients were retrospectively analyzed.The patients were divided into low red cell distribution width group,medium red cell distribution width group,and high red cell distribution width group(27 in each group).The in-hospital incidence of death,hemodynamics change and labotatory findings were compared among the 3 groups.Results The total in-hospital incidence of death,plasma N-terminal probrain natriutetic peptide(NT-proBNP) level increased with the elevated red cell distribution width in low,medium and high red cell distribution width groups(P<0.05).Pearson correlation analysis showed that age,systolic blood pressure,heart rate,NT-proBNP,troponin I and red cell distribution width were the relative factors for in-hospital death(P<0.05,P<0.01).Multivariate logistic regression analysis showed that age,systolic blood pressure and heart rate were the independent factors for in-hospital death(P<0.05,P<0.01).Conclusion The in-hospital incidence of death and shock increases in elderly acute pulmonary embolism patients with an elevated red cell distribution width.