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| 钩藤总碱、钩藤碱和异构藤碱的药理作用 | |
| 引用本文： | Shi JS,Yu JX,Chen XP,Xu RX. 钩藤总碱、钩藤碱和异构藤碱的药理作用[J]. Acta pharmacologica Sinica, 2003, 24(2): 97-101 |
| 作者姓名： | Shi JS Yu JX Chen XP Xu RX |
| 摘 要： | The pharmacvological actions of Uncaria alkaloids,rhyncopyline and isorhnchophyline extracted from Uncaria rhynchophylla Miq Jacks were reviewed.The alkaloids mainly act on cardiovascular system and central nervous system including the hypotension,brachycardia,antiarrhythmia,and protection of cerebral ischemia and sedation. The active mechanisms were related to blocking of calcium channel,opening of potassium channel,and regulating of nerve transmitters transport and metabolism,etc. |
| 关 键 词： | 药理作用 钩藤碱 异钩藤碱 植物药 钩藤总碱 |
Pharmacological actions of Uncaria alkaloids,rhynchophylline and isorhynchophylline |
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| Shi Jing-Shan,Yu Jun-Xian,Chen Xiu-Ping,Xu Rui-Xia. Pharmacological actions of Uncaria alkaloids,rhynchophylline and isorhynchophylline[J]. Acta pharmacologica Sinica, 2003, 24(2): 97-101 | |
| Authors: | Shi Jing-Shan Yu Jun-Xian Chen Xiu-Ping Xu Rui-Xia |
| Affiliation: | Department of Pharmacology, Zunyi Medical College, 563003, China. jsshi@zmc.gz.cn |
| Abstract: | The pharmacological actions of Uncaria alkaloids, rhynchophylline and isorhynchophylline extracted from Uncaria rhynchophylla Miq Jacks were reviewed. The alkaloids mainly act on cardiovascular system and central nervous system including the hypotension, brachycardia, antiarrhythmia, and protection of cerebral ischemia and sedation. The active mechanisms were related to blocking of calcium channel, opening of potassium channel, and regulating of nerve transmitters transport and metabolism, etc. |
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