宫颈环形电切术联合保妇康栓治疗宫颈上皮内瘤变的疗效观察

目的 探讨宫颈环形电切术(LEEP)联合保妇康栓治疗宫颈上皮内瘤变(CIN)的临床疗效.方法 将某院收治的CIN患者174例随机分为单纯手术组和联合治疗组,每组各67例.单缝手术组行LEEP术,联合治疗组在术后次月月经干净后使用保妇康栓,连用6d.将两组切下组织行病理检查,并与术前阴道镜病理检查的结果比较.观察术后阴道排液时间、创面愈合情况及并发症发生情况.结果 LEEP术后病理结果与阴道活检结果的符合率为77.6％.联合治疗组的阴道排液时间、创面愈合时间均显著低于单纯手术组,差异有统计学意义(P＜0.05).联合治疗组术后创面感染、宫颈管狭窄及宫颈管粘连等并发症的发生率均显著低于单纯手术组,差异有统计学意义(P＜0.05).结论 LEEP联合保妇康栓是治疗CIN一种安全有效的方法,可减少术后排液及术后并发症.

Clinical effect of loop electrosurgical excision procedure combined with Baofukang suppository in cervical intraepithelial neoplasia

OBJECTIVE To explore the clinical effect of loop electrosurgical excision procedure(LEEP)combined with Baofukang suppository in cervical intraepithelial neoplasia(CIN).METHODS 174 patients with CIN who were treated in our hospital were randomly divided into two groups.The single operation group(n = 67)was treated with LEEP alone,and the combined treatment group(n = 67)was treated with Baofukang suppository for six days after menstruation in the next month.The specimens cut by LEEP from the two groups were accepted pathological examination,and compared with preoperative diagnosis by biopsy under colposcopy.The vaginal fluiding time,the wound healing time and postoperative complications were observed.RESULTS The consistent rate of pathology diagnosis after LEEP and the preoperative diagnosis by biopsy under colposcopy were 77.6%.The vaginal fluiding time,the wound healing time in combined treatment group was significantly less than that in single operation group(P﹤0.05).There were significant differences in postoperative complications including wound infection,cervical canal stenosis and adhesion(P﹤0.05).CONCLUSION LEEP combined with Baofukang suppository in treating CIN is a safe and effective method,and it can greatly contribute to reduce vaginal fluiding time and postoperative complication.