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肝癌患者血清铜和锌浓度的变化
引用本文:袁振铎,徐婉珍,朱圭如. 肝癌患者血清铜和锌浓度的变化[J]. 首都医科大学学报, 1986, 7(4): 287
作者姓名:袁振铎  徐婉珍  朱圭如
作者单位:北京市临床医学研究所生化研究室(袁振铎,徐婉珍),北京市临床医学研究所生化研究室(朱圭如)
摘    要:
用原子吸收分光光度计测定了66例健康成年人及17例肝癌惠者血清铜和锌浓度。健康人血清铜平均浓度126.40±23.44μg/100ml((?)±SD),锌116.12±25.60μg/100ml.17例肝癌患者血清铜明显增高,平均浓度为155.83±37.08μg/100ml(P<0.001),血清锌降低为86.72±31.89μg/100ml(P<0.001)。血清Cu/Zn 比值明显的增加(正常值为1.12±0.32;肝癌时为2.15±0.31,P<0.001)。结果提示血清铜锌浓度及比值测定对诊断肝癌有一定意义。


Changes of Serum Copper and Zinc Conceatration in Patients With Hepatic Cancer
Yuan Zhenduo. Changes of Serum Copper and Zinc Conceatration in Patients With Hepatic Cancer[J]. Journal of Capital Medical University, 1986, 7(4): 287
Authors:Yuan Zhenduo
Affiliation:Beijing Clinical Medicine Research Institute
Abstract:
Serum copper and zinc of 66 healthy adults and 17 patients with hepaticcancer were determined by atomic absorption spectrophotometry.Themean concentration of serum copper in healthy blood donors and volunteerswas 126.40±23.44μg/100ml(X±S.D),and zinc was 116.12±25.60μg/100ml.Theconcentration of serum copper was markedly increased in 17 patientswith hapatic cancer,in which the mean serum copper was 155.83±37.08μg/100ml(P<0.001).Whereas,serum zinc decreased in great degree(86.72±31.89μg/100ml,P<0.001).Serum Cu/Zn ratio increasedconspicuously(1.12±0.30→2.15+0.31,P<0.001).
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