| 脂糖舒对正常和糖尿病小鼠胃肠推进运动的影响 |
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| 引用本文： | 舒思洁,明章银,刘彤云. 脂糖舒对正常和糖尿病小鼠胃肠推进运动的影响[J]. 浙江中西医结合杂志, 2001, 11(7): 414-415 |
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| 作者姓名： | 舒思洁 明章银 刘彤云 |
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| 作者单位： | 湖北省咸宁医学院药理教研室 咸宁 437100 |
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| 摘 要： | 目的：探讨脂糖舒对正常小鼠和糖尿病小鼠胃肠推进运动功能的影响及其作用机制。方法：采用正常小鼠和四氧嘧啶糖尿病模型小鼠整体胃排空试验和小肠推进试验，测定脂糖舒对两种不同状况下小鼠胃内残留率和小肠推进率，并将这些指标分别与乙酰胆碱、新斯的明和阿托品三药物比较。结果：脂糖舒除对正常小鼠胃排空无明显影响外（P＞0.05），对糖尿病小鼠的胃排空和对正常小鼠及糖尿病小鼠的小肠推进都有明显促进作用（P＜0.01）。结论：脂糖舒有一定的胃肠推进运动作用，其作用机制似乙酰胆碱或新斯的明。
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| 关 键 词： | 糖尿病 脂糖舒 胃肠推进运动 治疗 |
| 修稿时间： | 2001-02-13 |
Influence of Zhi-Tang-Shuon the Intestinal Movements in Normal and Diabetes Mice |
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| Shu Sijie,Ming Zhangyin,Liu Tongyun. Influence of Zhi-Tang-Shuon the Intestinal Movements in Normal and Diabetes Mice[J]. Zhejiang Journal of Integrated Traditional Chinese and Western Medicine, 2001, 11(7): 414-415 |
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| Authors: | Shu Sijie Ming Zhangyin Liu Tongyun |
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| Affiliation: | Shu Sijie,Ming Zhangyin,Liu Tongyun Department of pharmacology Xianning Medical college of Hubei province Xianning,437100 |
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| Abstract: | Objective:To exp1ore the effects of Zhi Tang Shu on the intestinal movements in normal diabetes mice.Methods:Animal diabetes models were employed to observe the movement of the stomach and intestines with the control of acetylcholine, neostigmine and atropine.Results:Zhi Tang Shu had no obvious effects on the movement of the intestines of the normal mice ( P >0.05). Improved intestinal movements were observed in diabetes mice ( P <0.0l).Conclusions:Zhi Tang Shu had the stimulating effects on the intestinal movements like acetylcholine and neostigmine. |
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| Keywords: | Zhi Tang Shu Diabetes Gastric movement mice |
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