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子宫内膜轻创术对拮抗剂方案体外受精治疗结局的改善
引用本文:刘杰,章汉旺,郑洁,雷亚兰,孙虹,李薇,夏敏. 子宫内膜轻创术对拮抗剂方案体外受精治疗结局的改善[J]. 中国妇幼保健, 2011, 26(36): 5757-5759
作者姓名:刘杰  章汉旺  郑洁  雷亚兰  孙虹  李薇  夏敏
作者单位:1. 华中科技大学同济医学院附属同济医院生殖医学中心 湖北武汉 430030
2. 湖北省妇幼保健院生殖医学中心
摘    要:目的:探讨子宫内膜轻创术对拮抗剂方案体外受精-胚胎移植临床妊娠率、胚胎种植率和活产率的影响。方法:回顾性分析2007年1月~2009年12月在该院生殖中心行拮抗剂方案体外受精-胚胎移植(IVF-ET)治疗的不孕症患者,促性腺激素(Gn)启动日B超显示子宫内膜回声异常或内膜厚度>5 mm的患者共69例,其中28例行子宫内膜轻创术者为研究组,41例未行轻创术者为对照组,比较两组患者临床妊娠率、胚胎种植率和活产率的差别。结果:两组患者平均年龄、不孕年限、基础FSH水平、Gn启动剂量、Gn使用天数、Gn总量、HCG日血E2水平、获卵数、受精数、可移植胚胎数和移植胚胎数均无统计学差异(P>0.05),研究组患者临床妊娠率、胚胎种植率和活产率分别为50.00%、28.13%和46.43%,虽然高于对照组的41.46%、23.47%和31.71%,但无统计学差异(P>0.05)。结论:子宫内膜轻创术并不能改善拮抗剂方案体外受精-胚胎移植的治疗结局。

关 键 词:体外受精-胚胎移植  拮抗剂  轻创术  妊娠结局

Effect of endometrial surgery with minimal damage on the outcome of in vitro fertilization with GnRH antagonists
LIU Jie,ZHANG Han-Wang,ZHENG Jie et al. Effect of endometrial surgery with minimal damage on the outcome of in vitro fertilization with GnRH antagonists[J]. Maternal and Child Health Care of China, 2011, 26(36): 5757-5759
Authors:LIU Jie  ZHANG Han-Wang  ZHENG Jie et al
Affiliation:LIU Jie,ZHANG Han-Wang,ZHENG Jie et al.Center of Reproductive Medicine,Tongji Hospital Affiliated to Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,Hubei,China
Abstract:Objective:To explore the effect of endometrial surgery with minimal damage on clinical pregnancy rate,embryo implantation rate and live birth rate of cases receiving in vitro fertilization-embryo transfer(IVF-ET) with GnRH antagonists.Methods:The patients with infertility who were treated with IVF-ET with GnRH antagonists in reproductive center of the hospital from January 2007 to December 2009 were analyzed retrospectively,B-type ultrasound showed that there were 69 patients with abnormality of endometrial...
Keywords:In vitro fertilization-embryo transfer  Antagonist  Surgery with minimal damage  Pregnancy outcome  
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