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Association of Atopy to Asthma Severity and Medication Use in Children |
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| Authors: | Christina D. Schwindt Thomas Tjoa Joshua N. Floro Christine Mclaren Ralph J. Delfino |
| Affiliation: | 1. Department of Pediatrics, University Children's Hospital, University of California, Irvine, Irvine, CA, USA;2. Division of Epidemiology, Department of Medicine, University of California, Irvine, Irvine, CA, USA |
| Abstract: | The importance of aeroallergens as triggers for asthma is well recognized, but the relationship between asthma severity and atopic profiles in childhood has not been elucidated. This study assessed the relationship of allergen sensitization to asthma severity in a study of 114 asthmatic children followed for 8 weeks in three Southern California areas. Increased controller medication and β-agonist use were positively associated with number of positive skin tests and allergy to mold and pollens. Mold was associated with increased asthma symptoms. Degree of atopy and reactivity to mold and pollens plays a significant role in asthma severity in asthmatic children. |
| Keywords: | allergens panel study epidemiology severity of illness index risk factors |