黛力新辅助治疗质子泵抑制剂治疗无效的非糜烂性反流病

目的 观察黛力新辅助治疗质子泵抑制剂治疗无效的非糜烂性反流病（NERD）的疗效。方法 64例患者按就诊顺序随机分为两组，对照组32例予雷贝拉唑10mg，每日2次；法莫替丁40mg，每晚1次。治疗组32例在对照组治疗基础上加用黛力新1粒，每天早上、中午各1次，治疗4周后进行疗效对比。结果 治疗组总有效率81．3％，明显优于对照组62．5％（P〈0．05）。结论 黛力新辅助雷贝拉唑、法莫替丁对质子泵抑制剂治疗无效的非糜烂性反流病有效。

Auxiliary therapy with Deanxit in patients of non-erosive reflux disease non-responding to proton pump inhibitor

Objective To observe the effectiveness of auxiliary therapy with Deanxit in patients of non-erosive reflux disease(NERD) who did not respond to proton pump inhibitor.Methods Sixty four NERD patients were randomly divided into two groups:the treatment group(n=32) and control group(n=32).Patients in control group were given with Rabeprazole 10mg twice a day,Famotidine 40mg every night.Patients in the treatment group were given the same drugs plus Deanxit(one tablet every morning and noon).The clinical outcomes of two groups were compared after 4 weeks.Results The effective rate in treatment group was 81.3%,while that was 62.5% in control group(P<0.05).Conclusion Auxiliary therapy of Deanxit combined with Rabeprazole and Famotidine is effective to NERD patients who did not respond to proton pump inhibitor.