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视黄醇结合蛋白4与冠心病的关系
引用本文:高璐,常志文,秦明照,陈晓燕. 视黄醇结合蛋白4与冠心病的关系[J]. 医药论坛杂志, 2010, 31(15)
作者姓名:高璐  常志文  秦明照  陈晓燕
作者单位:首都医科大学附属北京同仁医院干部医疗科,北京市,100730;首都医科大学附属北京同仁医院干部医疗科,北京市,100730;首都医科大学附属北京同仁医院干部医疗科,北京市,100730;首都医科大学附属北京同仁医院干部医疗科,北京市,100730
摘    要:目的研究视黄醇结合蛋白4(RPB4)与冠心病(CHD)之间的关系。方法研究对象78例,分为两组:正常对照组和冠心病组。测定血浆RPB4水平,采集有关数据。结果冠心病组血浆RPB4水平明显高于正常对照组[(44.72±16.98),(39.60±12.10),P<0.05]。相关分析显示血浆RBP4与腰围、腰臀比、BMI、TC、ln(TG)、FINS、FCP、ln(HOMA-IR)呈正相关。多元逐步回归分析,ln(TG)是血浆RBP4独立相关因素。结论血浆RBP4在冠心病的发病过程中起一定作用。

关 键 词:视黄醇结合蛋白4  冠状动脉疾病  相关性分析

Relationship between Retinol-Binding Protein 4 and Coronary Heart Disease
GAO Lu,CHANG Zhiwen,QIN Mingzhao,et al Beijing Tongren Hospital,Capital Medical University,Beijing ,China. Relationship between Retinol-Binding Protein 4 and Coronary Heart Disease[J]. Journal of Medical Forum, 2010, 31(15)
Authors:GAO Lu  CHANG Zhiwen  QIN Mingzhao  et al Beijing Tongren Hospital  Capital Medical University  Beijing   China
Affiliation:GAO Lu,CHANG Zhiwen,QIN Mingzhao,et al Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China
Abstract:Objective To investigate the relationship between the plasmal retinol-binding protein 4(RBP4)levels and coronary heart disease(CHD).Methods Totally 78 subjects were divided into two groups:controls(n=47)and patients with CHD(n=31),Plasmal RBP4 levels were measured by ELISA.Results Plasmal RBP4 levels in patients with CHD were significantly higher than that of controls.Plasmal RBP4 level was positively correlated with Waist,WHR,BMI,TC,ln(TG),FINS,FCP and ln(HOMA-IR).In a multiple stepwise regression analysis...
Keywords:Retinol-binding protein 4  Coronary disease  Relation analysis  
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