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| 原发性肾脏疾患红细胞及细胞免疫功能探讨 | |
| 引用本文： | 吴锦云 何士勤 等. 原发性肾脏疾患红细胞及细胞免疫功能探讨[J]. 江西医学院学报, 1994, 34(4): 37-40 |
| 作者姓名： | 吴锦云 何士勤 等 |
| 作者单位： | [1]江西医学院第二附属医院肾内科，南昌330006 [2]江西医学院微生物教研室，南昌330006 |
| 摘 要： | 分析40例不同原发性肾脏疾病患外周血红细胞C3b受体（RBC-C3b)、红细胞免疫复合物（RBC-IC）、T细胞亚群（CD3、CD4、CD8）及T淋巴细胞转化试验（LTT）结果。与正常人比较，RBC-C3b、CD3、CD4、CD8均下降，而RBC-IC则升高，尿毒症患血中LTT值下降明显，统计处理上述结果均有非常显差异（P<0.01)。各项指标作多因素相关分析发现，诸因素间存在某些相关性，提示原发性肾脏疾病患体内存在着多种免疫功能失调，且彼此影响是导致肾脏病发生的重要原因。 |
| 关 键 词： | 肾疾病 红细胞免疫学 免疫细胞 多因素分析 |
An Approach into Red-cell,T-cell Immune Function in Essential Renal Diseases |
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| Wu Jinyun,Hu Xin,Wu Wailao. An Approach into Red-cell,T-cell Immune Function in Essential Renal Diseases[J]. Acta Academiae Medicinae Jiangxi, 1994, 34(4): 37-40 | |
| Authors: | Wu Jinyun Hu Xin Wu Wailao |
| Abstract: | The C3b receptor of red blood cell(RBC-C3b),immune complex of red cell(RBC-IC),subgroups of T-cell(CD3,CD4,CD8 )and lymphocyte transformation test,in peripheralblood of patients with essential diseases of the kidney(40 cases)were reported and comparedwith those of normal suhjects. The results showed that the contents of RBC-C3b,T-cell sub-groups, were lower (P<0.01),and RBC-IC was higher (P<0. 01 )than those of normalsubtects. And the blood LTT in ureonic patients reduced evidently. Analysis of muItiple fac-tors revealed that thev were correlated to each other.It is suggested that imbalance of im-mune functions are present in patients with essential renal diseases and that their interactionis the important cause of kidney diseases. |
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