|
|||||
|
|
| 高频振荡机械通气治疗5例甲型H1N1流感患者呼吸衰竭的临床体会 | |
| 引用本文： | 张志刚,石斌,李斌,刘丽平,郭鸿,尹超,侯启亮. 高频振荡机械通气治疗5例甲型H1N1流感患者呼吸衰竭的临床体会[J]. 解放军医学杂志, 2011, 36(8): 800-803 |
| 作者姓名： | 张志刚 石斌 李斌 刘丽平 郭鸿 尹超 侯启亮 |
| 作者单位： | 兰州大学第一医院重症医学科,兰州,730000 |
| 摘 要： | 目的探讨高频振荡通气(HFOV)在甲型H1N1流感患者呼吸衰竭治疗中的应用价值及安全性。方法采用自身对照研究,5例呼吸衰竭甲型H1N1流感患者经常规机械通气(CMV)治疗无效后改用HFOV治疗,观察治疗前后血气[氧分压(PaO2)、二氧化碳分压(PCO2)、pH]、呼吸力学指标[氧浓度(FiO2)、平均气道压(Paw)、静态顺应(Cst)、氧合指数(PaO2/FiO2)]的变化,分析肺活检病理资料及临床治疗效果。结果经HFOV治疗后6~8h,3例患者氧合较前改善,24~48h后明显改善,48~72h后改为CMV,144h后成功脱机;2例患者经HFOV治疗,8h内病情恶化改用CMV治疗,1例75h后死亡,1例经体外膜氧合(ECMO)治疗145h后死亡。结论 HFOV可明显改善甲型H1N1流感呼吸衰竭患者的预后,与CMV序贯治疗可以降低并发症发生率病死率。 |
| 关 键 词： | 高频通气 流感病毒A型,H1N1亚型 呼吸功能不全 |
Clinical experience in treatment of five H1N1 flu patients with respiratory failure with high-frequency oscillatory mechanical ventilation |
|
| ZHANG Zhi-gang,SHI Bin,LI Bin,LIU Li-ping,GUO Hong,YIN Chao,HOU Qi-liang. Clinical experience in treatment of five H1N1 flu patients with respiratory failure with high-frequency oscillatory mechanical ventilation[J]. Medical Journal of Chinese People's Liberation Army, 2011, 36(8): 800-803 | |
| Authors: | ZHANG Zhi-gang SHI Bin LI Bin LIU Li-ping GUO Hong YIN Chao HOU Qi-liang |
| Affiliation: | ZHANG Zhi-gang,SHI Bin,LI Bin,LIU Li-ping,GUO Hong,YIN Chao,HOU Qi-liang.Department of Critical Care Medicine,First Hospital of Lanzhou University,Lanzhou 730000,China |
| Abstract: | Objective To investigate the application and safety of high-frequency oscillation ventilation(HFOV) in the treatment of patients suffering from H1N1 influenza with respiratory failure.Methods Self-control study was conducted.The treatment of five H1N1 influenza patients with respiratory failure was switched to HFOV after failure of conventional mechanical ventilation(CMV).Blood gas [partial pressure of oxygen(PaO2),partial pressure of carbon dioxide(PCO2),pH],respiratory mechanics indices [oxygen concentrat... |
| Keywords: | high-frequency ventilation influenza A virus H1N1 subtype respiratory insufficiency |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |