The effect of diet on intermediary metabolite concentrations in type 2 (non-insulin-dependent) diabetes mellitus |
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| Authors: | Sheppard M. C. Burrin J. Alberti K. G. M. M. Nattrass M. |
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| Affiliation: | (1) General Hospital, Birmingham;(2) Department of Clinical Biochemistry, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK |
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| Abstract: | ![]()
Summary The metabolic response to a standard meal was studied in six Type 2 (non-insulin-dependent) diabetic patients at diagnosis and following 4–6 weeks of dietary treatment. The fall in blood glucose concentration following treatment was accompanied by significant reductions in circulaitng concentrations of lactate, pyruvate, alanine and glycerol. Blood 3-hydroxybutyrate concentrations also fell with treatment. |
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| Keywords: | Type 2 (non-insulin-dependent) diabetes diet blood glucose lactate pyruvate alanine glycerol 3-hydroxybutyrate |
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