| 急性心肌梗塞患者外周血IL-2、sIL-2R水平及动态变化的研究 |
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| 引用本文： | 朱宇清,许政刚,傅研,张京秀,李清朗.急性心肌梗塞患者外周血IL-2、sIL-2R水平及动态变化的研究[J].心肺血管病杂志,1998(4). |
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| 作者姓名： | 朱宇清 许政刚 傅研 张京秀 李清朗 |
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| 作者单位： | 北京同仁医院急诊科!100730(朱宇清，许政刚，傅研，李清朗)，北京同仁医院检验科!100730(张京秀) |
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| 摘 要： | 本文测定了30例急性心肌梗塞患者外周血白细胞介素2（IL-2）及其游离受体（sIL-2R）水平，并进行动态观察，实验结果表明，发病后48h内IL-2水平最低，而sIL-2R水平最高，与正常对照组比较有显著性差异（P＜0.001）；发病后72hIL-2水平开始升高，sIL-2R水平开始下降，至2～3周时两者水平逐渐趋于正常，与对照组比较无显著性差异（P＞0．05）。研究表明急性心肌梗塞与机体免疫应答密切相关。
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| 关 键 词： | 急性心肌梗塞（AMI） 白细胞介素2（IL-2） 可溶性白细胞介素2受体（sIL-2R） |
Study of Changes of the Levels of Serum IL-2,sIL-2R in Patients with Acute Myocardial Infarction |
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| Zhu Yuqing, Xu Zhenggang, Fu Yan,et al..Study of Changes of the Levels of Serum IL-2,sIL-2R in Patients with Acute Myocardial Infarction[J].Journal of Cardiovascular and Pulmonary Diseases,1998(4). |
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| Authors: | Zhu Yuqing Xu Zhenggang Fu Yan |
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| Institution: | Zhu Yuqing, Xu Zhenggang, Fu Yan, et al. |
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| Abstract: | The levels of serum interleukin - 2 (IL - 2) and soluble interleukin - 2 recepter (sIL - 2R) of 30 Patients with acute myocardial infarction (AMI) was studied and their developments Observed. The results showed that,the level of IL- 2 is lowest on the second day after attack in AMI group, while the level of sIL - 2R is the highest (P<0. 001 ). The level of IL-2 began to increase and sIL -2R level have began to decrease from the 3rd day after AMI. Both IL - 2 level and sIL - 2R level have no prominant difference between AMI Patients and the control groups from the 14th day to the 21th day after AMI (P >0.05). Our conclusion confirms that AMI is closely related to the immunoreaction system. |
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| Keywords: | Acute myocardial infarction (AMI) Interleukin-2 (IL-2) Soluble interleukin-2 recepter (sIL-2R) |
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