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急性脑梗死患者治疗前后血清Hcy和hs-CRP检测的临床意义
引用本文:臧志忠,潘生英,徐树平,王军. 急性脑梗死患者治疗前后血清Hcy和hs-CRP检测的临床意义[J]. 放射免疫学杂志, 2007, 20(5): 458-460
作者姓名:臧志忠  潘生英  徐树平  王军
作者单位:江苏省丹阳市人民医院神经内科,212300;南京市第一人民医院神经内科
摘    要:
目的:探讨了急性脑梗死患者治疗前后血清同型半胱氨酸(Hcy)和超敏C-反应蛋白(hs-CRP)水平的变化及意义.方法:应用免疫比浊法和化学发光法对40例急性脑梗死患者进行了血清Hcy和hs-CRP水平检测,并与35名正常健康人作比较.结果:在治疗前急性脑梗死患者血清Hcy和hs-CRP水平非常显著地高于正常人组(P<0.01),且与梗死灶面积呈正相关(P<0.05),经治疗后一周则与正常人组比较无显著差异(P>0.05).结论:检测急性脑梗死患者血清Hcy和hs-CRP水平的变化对判断病情和评价疗效均具有重要的临床价值.

关 键 词:急性脑梗死  同型半胱氨酸  超敏C反应蛋白
收稿时间:2007-07-25
修稿时间:2007-07-25

Clinical Significance of Determination of Changes of Serum Hcy and hs-CRP Levels After Treatment in Patients with Acute Cerebral Infarction
Cang Zhizhong, Pan Shengying, Xu Shuping,et al.. Clinical Significance of Determination of Changes of Serum Hcy and hs-CRP Levels After Treatment in Patients with Acute Cerebral Infarction[J]. Journal of Radioimmanology, 2007, 20(5): 458-460
Authors:Cang Zhizhong   Pan Shengying   Xu Shuping  et al.
Abstract:
Objective To investigate the changes of serum Hcy and hs-CRP levels after treatment in patients with acute cerebral infarction.Methods Serum hs-CRP(with immunoturbidity method),and Hcy(with chemiluminescence) levels in 40 patients with cerebral infarction both before and after treatment as well as 35 controls.Results Before treatment,serum Hcy and hs-CRP levels were significantly higher in the patients than those in controls(P<0.01),Moreover,the levels were positively correlated with the size of the infarction(P<0.05).After treatment for one week,the serum Hcy,hs-CRP levels were not significantly different from those in controls(P>0.05).Conclusion Detection of serum Hcy and hs-CRP levels was helpful for the perdiction of treatment efficacy.
Keywords:acute cerebral infarction  homocysteine(Hcy)  high sensitive C-reactive protein(hs-CRP)
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