3D打印技术在儿童腹膜后神经母细胞瘤血管骨骼化手术中的应用价值探讨

Objective To explore the value of three-dimensional（3D）printing in vascular skeletal surgery for children with retroperitoneal neuroblastoma. Methods From January 2016 to June 2018, hospitalized children with retroperitoneal neuroblastoma fulfilling the inclusion criteria were divided into 3D and non-3D print groups according to whether 3D tumor model was printed preoperatively. Tumor size, operative duration, surgical resection rate and complication rate were recorded. Family members responded to a questionnaire and the results were statistically analyzed. Results For 15 children in 3D printing group, there were 7 boys and 8 girls with an average age of （40. 5 ± 28. 6） months；for 25 children in non-3D printing group, there were 13 boys and 12 girls with an average age of （43. 3 ± 24. 8）months. 3D model could delineate a distinct relationship between tumor, adjacent organs and blood vessels. All of them successfully underwent vascular skeletal tumor resection. No significant inter-group differences existed in gender, age, tumor stage size, number of tumorinvaded vessel, surgical resection rate, complication rate, postoperative recurrence or survival rate (P >0.05). In non-3D printing group (P <0.05), family members' scores on the degree of disease mastery were significantly higher than those in non-3D printing group (P < 0. 05). Conclusion 3D printing tumor model can distinctly delineate the complex anatomical relationship of retroperitoneal neuroblastoma in children. And it is conducive for preoperative planning, shortening operative duration and improving the awareness of family members on surgical approaches and patient-physician rapports. © 2019 The Authors.

Application of three-dimensional printing technology in vascular skeletal surgery for children with retroperitoneal neuroblastoma

Yang Chao;Wang Shan;Li Changchun;Zhang Jun;Zhao Zhenzhen;Kong Xiangru;Deng Xiaobin;Peng Liang;Du Yifei(Department of Pediatric Surgical Oncology,Affiliated Children's Hospital,Chongqing Medical University,Ministry of Education Key Laboratory of Child Development & Disorders,Chongqing International Science & Technology Cooperation Center for Child Development & Disorders,Key Laboratory of Pediatrics in Chongqing,Chongqing 400014,China)