| 基于糖代谢、脂代谢和能量代谢探讨脾脏与阿尔茨海默病的关系 |
| |
| 引用本文： | 郑琴,罗俊,章德林,唐宇,朱梅芳,汤丹丰,吴海霞,郭园园.基于糖代谢、脂代谢和能量代谢探讨脾脏与阿尔茨海默病的关系[J].中国实验方剂学杂志,2020,26(5):178-185. |
| |
| 作者姓名： | 郑琴 罗俊 章德林 唐宇 朱梅芳 汤丹丰 吴海霞 郭园园 |
| |
| 作者单位： | 江西中医药大学 现代中药制剂教育部重点实验室, 创新药物与高效节能降耗制药设备国家重点实验室, 南昌 330004,江西中医药大学 现代中药制剂教育部重点实验室, 创新药物与高效节能降耗制药设备国家重点实验室, 南昌 330004,江西中医药大学 现代中药制剂教育部重点实验室, 创新药物与高效节能降耗制药设备国家重点实验室, 南昌 330004,江西中医药大学 现代中药制剂教育部重点实验室, 创新药物与高效节能降耗制药设备国家重点实验室, 南昌 330004,江西中医药大学 现代中药制剂教育部重点实验室, 创新药物与高效节能降耗制药设备国家重点实验室, 南昌 330004,江西中医药大学 现代中药制剂教育部重点实验室, 创新药物与高效节能降耗制药设备国家重点实验室, 南昌 330004,江西中医药大学 现代中药制剂教育部重点实验室, 创新药物与高效节能降耗制药设备国家重点实验室, 南昌 330004,江西中医药大学 现代中药制剂教育部重点实验室, 创新药物与高效节能降耗制药设备国家重点实验室, 南昌 330004 |
| |
| 基金项目： | 国家自然科学基金项目（81860874）；江西省科技创新人才重点项目（20171BCB18001）；江西省教育厅科学技术研究重点项目（GJJ170699） |
| |
| 摘 要： | 阿尔茨海默病(AD)是一种慢性神经退行性疾病,严重影响着人们的生活。到目前为止,AD的病因尚不明确,使得其预防和治疗成为世界性的难题。已有研究表明AD可能是一种代谢性疾病,与糖脂代谢和能量代谢有关。中医认为,"脾为后天之本,气血生化之源",不仅与机体物质代谢、能量代谢密切相关,还与人体的衰老密切联系。该文拟分析代谢与AD,脾与代谢之间的关系,以及健脾方对AD的作用,旨在从调控代谢的角度,分析中医"从脾论治"治疗AD的可能机制,挖掘健脾中药在治疗或预防AD中的潜在价值,为探索AD的药物研制和中医疗法提供新思路。
|
| 关 键 词： | 糖代谢 脂代谢 能量代谢 阿尔茨海默病 脾脏 中医药 线粒体 |
| 收稿时间： | 2019/3/12 0:00:00 |
Investigation of Relationship Between Spleen and Alzheimer's Disease Based on Glucose, Lipid and Energy Metabolisms |
| |
| ZHENG Qin,LUO Jun,ZHANG De-lin,TANG Yu,ZHU Mei-fang,TANG Dan-feng,WU Hai-xia and GUO Yuan-yuan.Investigation of Relationship Between Spleen and Alzheimer's Disease Based on Glucose, Lipid and Energy Metabolisms[J].China Journal of Experimental Traditional Medical Formulae,2020,26(5):178-185. |
| |
| Authors: | ZHENG Qin LUO Jun ZHANG De-lin TANG Yu ZHU Mei-fang TANG Dan-feng WU Hai-xia and GUO Yuan-yuan |
| |
| Institution: | State Key Laboratory of Innovative Drug and Efficient Energy-Saving Pharmaceutical Equipment, Key Laboratory of Modern Chinese Medicine Preparations, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China,State Key Laboratory of Innovative Drug and Efficient Energy-Saving Pharmaceutical Equipment, Key Laboratory of Modern Chinese Medicine Preparations, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China,State Key Laboratory of Innovative Drug and Efficient Energy-Saving Pharmaceutical Equipment, Key Laboratory of Modern Chinese Medicine Preparations, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China,State Key Laboratory of Innovative Drug and Efficient Energy-Saving Pharmaceutical Equipment, Key Laboratory of Modern Chinese Medicine Preparations, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China,State Key Laboratory of Innovative Drug and Efficient Energy-Saving Pharmaceutical Equipment, Key Laboratory of Modern Chinese Medicine Preparations, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China,State Key Laboratory of Innovative Drug and Efficient Energy-Saving Pharmaceutical Equipment, Key Laboratory of Modern Chinese Medicine Preparations, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China,State Key Laboratory of Innovative Drug and Efficient Energy-Saving Pharmaceutical Equipment, Key Laboratory of Modern Chinese Medicine Preparations, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China and State Key Laboratory of Innovative Drug and Efficient Energy-Saving Pharmaceutical Equipment, Key Laboratory of Modern Chinese Medicine Preparations, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China |
| |
| Abstract: | |
| |
| Keywords: | glucose metabolism lipid metabolism energy metabolism Alzheimer''s disease spleen traditional Chinese medicine mitochondria |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《中国实验方剂学杂志》浏览原始摘要信息 |
| 点击此处可从《中国实验方剂学杂志》下载免费的PDF全文 |
|
