| miRNA与肿瘤转移调控机制的研究进展 |
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| 引用本文： | 黄永塔(综述,莫祥兰(审校. miRNA与肿瘤转移调控机制的研究进展[J]. 中国临床新医学, 2020, 13(1): 94-98 |
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| 作者姓名： | 黄永塔(综述 莫祥兰(审校 |
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| 作者单位： | 530021 南宁,广西壮族自治区人民医院病理科 |
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| 基金项目： | 国家自然科学基金项目（编号：81360355）;广西卫健委科研课题（编号：Z2013355,Z2016590） |
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| 摘 要： | 转移是恶性肿瘤的基本特征和重要标志,也是癌症患者治疗失败或死亡的首要原因.微小核糖核酸[micro ribonucleic acid(microRNA, miRNA)]是一类具有调控功能的非编码RNA片段,通过调控下游靶基因的转录和翻译,在肿瘤发生发展过程中发挥重要作用. miRNA参与恶性肿瘤侵袭及转移生物学行为中的...
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| 关 键 词： | 微小核糖核酸 肿瘤 转移 调控机制 |
| 收稿时间： | 2019-02-28 |
Research progress of regulation mechanisms in miRNA and tumor metastasis |
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| HUANG Yong-t,MO Xiang-lan. Research progress of regulation mechanisms in miRNA and tumor metastasis[J]. Chinese Journal of New Clinical Medicine, 2020, 13(1): 94-98 |
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| Authors: | HUANG Yong-t MO Xiang-lan |
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| Affiliation: | (Department of Pathology,the People′s Hospital of Guangxi Zhuang Autonomous Region,Nanning 530021,China) |
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| Abstract: | Metastasis is the basic characteristics and important signs of malignant tumors,and also the primary cause of treatment failure or death of cancer patients.Micro ribonucleic acid(microRNA,miRNA)is a kind of non-coding RNA fragments with regulatory function.It plays an important role in tumorigenesis and development by regulating the transcription and translation of downstream target genes.miRNA plays an important role in the multiple important links in biological behavior of invasion and metastasis of malignant tumors.Elucidating the mechanisms of metastasis regulation of miRNA related to tumor metastasis will provide us with a new perspective on the occurrence and development of tumors and bring about a new breakthrough in the diagnosis and treatment of cancers.In this paper,we review the research progress of the regulation mechanisms in miRNA and tumor metastasis. |
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| Keywords: | Micro ribonucleic acid(microRNA miRNA) Tumors Metastasis Regulation mechanisms |
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