非溃疡性消化不良飞行员胃运动功能的改变

目的　对患有非溃疡性消化不良的飞行人员进行胃排空功能检测。　方法　采用双核素标记试餐及单光子发射计算机体层摄影 (SPECT)技术 ,对 5 4例非溃疡性消化不良 (NUD)飞行员(其中包括类溃疡型 2 3例 ,运动障碍型 2 6例 ,返流型 5例 )和 6 4例健康飞行员进行胃排空测定 ,求出各自全胃半排空时间 (T1 /2 ) ,近端胃半排空时间 (PT1 /2 ) ,固体食物开始排空前的延迟时间 (T1 )及其异常的发生率。　结果　与对照组相比 ,NU D组飞行员液体 T1 /2 延长 ,与 3型 NU D间均无明显关系 ;固体 T1 /2 明显延长 ,异常发生率 72 .2 % ,与运动障碍型 NUD和返流型 NU D呈正相关 (r=0 .81和 0 .78,P<0 .0 5 ) ;PT1 /2 与类溃疡型 NUD呈正相关 (r=0 .75 ,P<0 .0 5 ) ;T1 异常发生率 88.9% ,其中38.2 %延迟 ,与运动障碍型 NU D呈正相关 (r=0 .78,P<0 .0 5 ) ,另 6 1.8% T1 消失 ,与类溃疡型 NU D呈负相关 (r=- 0 .6 7,P<0 .0 5 )。　结论　 NUD飞行员多有固体食物排空障碍。

A study on gastric motility function in pilots with nonulcer dyspepsia

Objective To explore the change of gastric motility function in pilots with nonulcer dyspepsia (NUD). Methods Fifty four pilots with NUD (including dyskinesia type 26, ulceroid type 23, and reflux type 5) served as subjects, and 64 healthy pilots as controls. They underwent gastric emptying tests using dual isotope labeled liquid and solid test meals and single photon emission computer tomography (SPECT). Half emptying time of whole stomach (T 1/2 ), and its proximal part (PT 1/2 ), as well as lag time (T 1) before emptying were obtained and compared. Results As compared with controls, T 1/2 of liquid meal in NUD pilots was longer, but showed no significant relationship with 3 types; T 1/2 of solid meal in NUD pilots was significantly longer. The incidence of abnormal gastric emptying was 72 2%, and was significantly related with dyskinesia type and reflux type ( r =0.81, 0.78, respectively, P <0.05). The incidence of abnormal T 1 (88.9%) in NUD pilots was significantly higher than those of controls, including T 1 delay 38.2% positively related with dyskinesia type ( r=0.78, P <0.05) and T 1 disappear 61.8%, negatively related with ulceroid type ( r=-0.67, P <0.05). Conclusions Pilots with NUD have a high incidence of gastric emptying disturbance of solid meal.