Research priorities for diarrhoeal disease vaccines: memorandum from a WHO meeting.

Diarrhoeas caused by rotaviruses, Shigella, Vibrio cholerae, and enterotoxigenic Escherichia coli (ETEC) represent a major health burden in developing countries, and have stimulated much effort towards vaccine development in order to protect against these four disease agents. This Memorandum describes the state of the art and points the way to future research and test trials in this area.