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复方氨基酸胶囊纠正慢性肾功能衰竭血液透析伴低蛋白血症的疗效观察
引用本文:傅鹏,袁伟杰. 复方氨基酸胶囊纠正慢性肾功能衰竭血液透析伴低蛋白血症的疗效观察[J]. 中国药房, 2005, 16(10): 764-766
作者姓名:傅鹏  袁伟杰
作者单位:第二军医大学附属长海医院,上海市,200433
摘    要:目的:观察复方氨基酸胶囊纠正慢性肾功能衰竭血液透析伴低蛋白血症的疗效。方法:30例慢性肾功能衰竭血液透析伴低蛋白血症患者口服复方氨基酸胶囊(0. 35g/粒)2粒,2次/d ,连用12wk ,比较治疗前和治疗后肝、肾功能及血浆白蛋白、血浆前白蛋白的变化。结果:治疗前、后血浆白蛋白分别为(30. 5±4. 6)、(35 .9±7. 1)g/L(P<0. 05) ;治疗前、后血浆前白蛋白分别为(213. 0±46. 9)、(275. 8±52 .3)mg/L(P<0. 05)。治疗前、后患者肝、肾功能无显著变化,且服药过程中无1例发生任何不良反应。结论:复方氨基酸胶囊用于纠正慢性肾功能衰竭血液透析患者的低蛋白血症安全、有效。

关 键 词:复方氨基酸胶囊  低蛋白血症  慢性肾功能衰竭  血液透析
文章编号:1001-0408(2005)10-0764-03
修稿时间:2005-02-21

Effects of Compound Amino Acids Capsules on Hypoalbuminemia in Patients with Chronic Renal Failure Undergoing Hemodialysis
FU Peng,YUAN Weijie. Effects of Compound Amino Acids Capsules on Hypoalbuminemia in Patients with Chronic Renal Failure Undergoing Hemodialysis[J]. China Pharmacy, 2005, 16(10): 764-766
Authors:FU Peng  YUAN Weijie
Abstract:OBJECTIVE:To evaluate the effects of compound amino acids capsul es on hypoalbuminemia in patients with chronic renal failure undergoing hemodialysis.METHODS:30hemodialysis patients were selected to orally take2compound amino acids capsules(0.35g per capsule)twice daily for12weeks,renal and liver function and levels of serum albumin and pre-albumin were measured before and after the experiment.RESULTS:The levels of serum albumin and pre-albumin were increased significantly after the treatment,it were(30.5±4.6)g/L vs(35.9±7.1)g/L,and(213.0±46.9)mg/L vs(275.8±52.3)mg/L respectively(P<0.05).There was not any side-effect during the therapy and the renal and liver function of paˉtients remained stable.CONCLUSION:Compound amino acid capsules safely and effectively correct hypoalbuminemia in hemodialysis patients with chronic renal failure.
Keywords:Compound amino acids capsules  Hypoalbuminemia  Chronic renal failure  Hemodialysis
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