Modiolides A and B,two new 10-membered macrolides from a marine-derived fungus |
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Authors: | Tsuda Masashi Mugishima Takao Komatsu Kazusei Sone Teruo Tanaka Michiko Mikami Yuzuru Kobayashi Jun'ichi |
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Affiliation: | Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan. |
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Abstract: | Two new 10-membered macrolides, modiolides A (1) and B (2), and a new linear pentaketide, modiolin (3), were isolated from the cultured broth of a fungus Paraphaeosphaeria sp. (N-119), which was separated from a marine horse mussel, and the structures were elucidated by spectroscopic data. |
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