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Applying Mendelian randomization to appraise causality in relationships between nutrition and cancer |
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| Authors: | Wade Kaitlin H Yarmolinsky James Giovannucci Edward Lewis Sarah J Millwood Iona Y Munafò Marcus R Meddens Fleur Burrows Kimberley Bell Joshua A Davies Neil M Mariosa Daniela Kanerva Noora Vincent Emma E Smith-Byrne Karl Guida Florence Gunter Marc J Sanderson Eleanor Dudbridge Frank Burgess Stephen Cornelis Marilyn C Richardson Tom G Borges Maria Carolina Bowden Jack Hemani Gibran Cho Yoonsu Spiller Wes Richmond Rebecca C Carter Alice R Langdon Ryan Lawlor Deborah A Walters Robin G Vimaleswaran Karani Santhanakrishnan Anderson Annie Sandu Meda R Tilling Kate Davey Smith George Martin Richard M Relton Caroline L |
| Institution: | 1.Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK ;2.Medical Research Council (MRC) Integrative Epidemiology Unit (IEU) at the University of Bristol, Bristol, UK ;3.Departments of Nutrition and Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA ;4.Bristol National Institute for Health Research (NIHR) Biomedical Research Centre, Bristol, UK ;5.Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU) and the Medical Research Council Population Health Research Unit (MRC PHRU), Nuffield Department of Population Health, University of Oxford, Oxford, UK ;6.School of Psychological Science, University of Bristol, Bristol, UK ;7.Department of Economics, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands ;8.Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, The Netherlands ;9.K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway ;10.International Agency for Research On Cancer (IARC), Lyon, France ;11.Nightingale Health Oy, Helsinki, Finland ;12.Cellular and Molecular Medicine, Faculty of Life Sciences, University of Bristol, Bristol, UK ;13.Department of Health Sciences, University of Leicester, Leicester, UK ;14.MRC Biostatistics Unit, University of Cambridge, Cambridge, UK ;15.Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK ;16.Northwestern University Feinberg School of Medicine, Chicago, IL, USA ;17.Research Innovation Learning and Development (RILD) Building, University of Exeter Medical School, Exeter, UK ;18.Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading, UK ;19.Population Health and Genomics, School of Medicine, University of Dundee, Dundee, Scotland, UK ;20.NIHR Biomedical Research Centre, Bristol, UK ; |
| Abstract: | Cancer Causes & Control - Dietary factors are assumed to play an important role in cancer risk, apparent in consensus recommendations for cancer prevention that promote nutritional changes.... |
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