|
|||||
|
|
EEG alpha photic driving abnormalities in chronic schizophrenia |
|
| Authors: | Daniel M. Rice Steven G. Potkin Yi Jin Robert Isenhart C. W. Chris Heh John Sramek Jerome Costa Curt A. Sandman |
| Affiliation: | a Daniel M. Rice, Ph.D., is NIH Postdoctoral Fellow, Brain Imaging Center, Department of Psychiatry and Human Behavior, University of California, Irvine, USA b Steven G. Potkin, M.D., is Professor, Department of Psychiatry and Human Behavior, University of California, Irvine, USA c Yi Jin, M.D., is Research Associate Department of Psychiatry and Human Behavior, University of California, Irvine, USA d Robert Isenhart is Research Associate Department of Psychiatry and Human Behavior, University of California, Irvine, USA e C.W. Chris Heh, M.D., is Assistant Clinical Professor, Department of Psychiatry and Human Behavior, University of California, Irvine, USA f Curt A. Sandman, Ph.D., is Professor-in-Residence, Department of Psychiatry and Human Behavior, University of California, Irvine, USA g John Sramek, Pharm.D., is Director of Research, Hospital, Norwalk, CA, USA h Jerome Costa, M.D., is Staff Psychiatrist at Metropolitan State Hospital, Norwalk, CA, USA |
| Abstract: | Periodic photic stimuli across the entire electroencephalographic (EEG) frequency range were used in an attempt to assess EEG functional differences between chronic schizophrenic patients and control subjects. The EEG responses to these photic stimuli were significantly attenuated in the schizophrenic patients, specifically at the frequencies within the EEG alpha range. The schizophrenic patients also showed an alpha range attenuation in the “no stimulus” EEG alpha measure, such that there was a significant correlation across subjects between the “stimulus” and “no stimulus” EEG alpha range abnormalities. These abnormalities are discussed with reference to possible dysfunctional thalamic mechanisms involved in the pacing of EEG alpha activity and the gating of information through the cerebral cortex. |
| Keywords: | Electroencephalographic (EEG) alpha rhythm schizophrenia EEG photic driving thalamus |
| 本文献已被 ScienceDirect 等数据库收录！ | |