思美泰治疗酒精性肝病疗效观察

目的　观察思美泰粉针剂对酒精性肝病的疗效和安全性。方法　将临床确诊为酒精性肝病的 12 0例门诊或住院病人随机分为两组 ,治疗组给予思美泰 1 0g每日一次静点 ,对照组给予维生素C 2 0g、维生素B60 2g静点 ,疗程 2 0天。结果　治疗组失访 4例 ,对照组失访 6例。治疗组显效率 5 3 6 %,总有效率为 80 4 %;对照组显效率为 38 9%,总有效率为 74 1%。两组比较 ,治疗组显效率明显高于对照组 (t =2 6 0 ,P <0 0 5 ) ,两组总有效率无显著性差异 (t=1 5 5 ,P >0 10 )。两组均未见明显不良反应。结论思美泰粉针剂治疗酒精性肝病有较好疗效。

Observation of the effect of S-adenosyl-L-methionine on alcoholic liver disease

Aim To observe the effect and safety of S-adenosyl-L-methionine injection on treating alcoholic liver disease.Methods 120 cases of patients who were clearly diagnosed of alcoholic liver disease were randomly divided into two groups,and the treating group was given S-adenosyl-L-methionine injection 1.0g each day,the control group was given Vitamin C 2.0g and Vitamin B 6 0.2g injection each day.The therapy period lasted for 20 days.Results 4 cases in treating group and 6 in control group were lost for tracing.Notable efficacy rate in treating group was 53.6%,which was significantly higher than the control group (38.9%),total efficacy rate in treating group was 80.4%,while it was 74.1% in control group,and there was no significant difference between them.No marked side effects were found in both groups.Conclusions S-adenosyl-L-methionine injection is an effective drug in treating alcoholic liver disease.