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| PML/RARa阴性伴复杂核型染色体改变的急性早幼粒细胞白血病(APL)一例 | |
| 引用本文： | 赵丽菲,张小卿. PML/RARa阴性伴复杂核型染色体改变的急性早幼粒细胞白血病(APL)一例[J]. 辽宁中医药大学学报, 2012, 0(3): 205-206 |
| 作者姓名： | 赵丽菲 张小卿 |
| 作者单位： | 中国人民解放军第202医院检验科;辽宁中医药大学针灸推拿学院 |
| 摘 要： | 急性早幼粒细胞白血病(APL)是急性白血病的一种特殊类型。全反式维甲酸(ATRA)、三氧化二砷相继应用于APL的治疗,使其成为急性髓系白血病中治愈率最高的一个亚型;而PML/RARa阴性伴复杂核型染色体改变的急性髓系白血病M3型则属于高危预后。 |
| 关 键 词： | 急性早幼粒细胞白血病 PML/RARa融合基因阴性 染色体核型改变 |
One Case of PML/Rara Fusion Gene-Negative Chromosomal Changes Associated With Complex Karyotypes of Acute Promyelocytic Leukemia |
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| ZHAO Li-Fei,ZHANG Xiao-Qing. One Case of PML/Rara Fusion Gene-Negative Chromosomal Changes Associated With Complex Karyotypes of Acute Promyelocytic Leukemia[J]. Journal of Liaoning University of Traditional Chinese Medicine, 2012, 0(3): 205-206 | |
| Authors: | ZHAO Li-Fei ZHANG Xiao-Qing |
| Affiliation: | 1.Department Laboratory Medicine of People’s Liberation Army No.202 Hospital,Shenyang 110003,Liaoning,China;2.College of Acupuncture and Moxibustion,Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China) |
| Abstract: | Acute promyelocytic leukemia(APL)is a special type of acute leukemia.All-trans retinoic acid(ATRA),arsenic trioxide have been used in the treatment of APL,to become acute myeloid leukemia,a subtype of the highest cure rate.But PML / RARa negative chromosomal changes associated with complex karyotypes of acute myeloid leukemia M3 type belong to high-risk prognostic. |
| Keywords: | acute promyelocytic leukemia PML / RARa fusion gene-negative karyotype change |
| 本文献已被 CNKI 等数据库收录！ | |