Interaction between the structural glycoprotein of connective tissue and proteoglycans and glycosaminoglycans

Structural glycoprotein (SGP) of connective tissue isolated from bovine heart valves and nasal septal cartilage forms water-soluble complexes with protein-chondroitin-4-sulfate and with various fractions of heparin. SGP does not form these complexes with hyaluronic acid. It is postulated that this phenomenon plays an important role in the formation of collagen and elastic fibers.Institute of Rheumatism, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR S. S. Debov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 82, No. 12, pp. 1430–1432, December, 1976.