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| 鱼油多不饱和脂肪酸对人血小板、红细胞必需脂肪酸组成以及过氧化-抗氧化能力的影响 | |
| 引用本文： | 王建中,朱瑞龙,邱仁芳,陈松鹤,应赛亚. 鱼油多不饱和脂肪酸对人血小板、红细胞必需脂肪酸组成以及过氧化-抗氧化能力的影响[J]. 中国医药工业杂志, 1992, 0(2) |
| 作者姓名： | 王建中 朱瑞龙 邱仁芳 陈松鹤 应赛亚 |
| 作者单位： | 上海东海制药厂研究室 上海200090(王建中，朱瑞龙，邱仁芳)，上海中山医院内科 上海200032(陈松鹤，应赛亚) |
| 摘 要： | 随着年龄增加,人血小板、红细胞膜脂质中 EPA、DHA 减少,而 AA 增加,同时 MDA 的生成增多,SOD 的活性降低。红细胞与 LDL 温育可增强此过程,但与 EPA 温育则可抑制 LDL 的作用。老年志愿者服用鱼油多不饱和脂肪酸4周,6g/d,见红细胞膜中 EPA、DHA 增加、AA 降低、MDA 的生成减少,SOD活性增加。提示血液份必需脂肪酸的组成对过氧化-抗氧化的平衡有重要影响,鱼油是潜在的抗衰老药物。 |
| 关 键 词： | 鱼油 廿碳五烯酸 廿二碳六烯酸 丙二醛超氧化物歧化酶 |
EFFECT OF FISH OIL FATTY ACIDS ON MALONDIALDEHYDE AND SUPEROXIDE DISMUTASE IN PLATELETS AND ERYTHROCYTES OF HUMAN VOLUNTEERS |
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| WANG Jian-Zhong ZHU Rui-Long QIU Ren-Fang CHEN Song-Hea. EFFECT OF FISH OIL FATTY ACIDS ON MALONDIALDEHYDE AND SUPEROXIDE DISMUTASE IN PLATELETS AND ERYTHROCYTES OF HUMAN VOLUNTEERS[J]. , 1992, 0(2) | |
| Authors: | WANG Jian-Zhong ZHU Rui-Long QIU Ren-Fang CHEN Song-Hea |
| Affiliation: | WANG Jian-Zhong ZHU Rui-Long QIU Ren-Fang CHEN Song-He~a |
| Abstract: | In healthy volunteers,the composition of fatty acids in plate-lets and erythrocytes were determined.AA and MDA increased(P<0.05),EPA,DHA and the activity of SOD were reduced with age.Incubation with LDLcould promote,and incubation with EPA inhibit,the process.Administration offish oil fatty acids to old volunteers caused increase in EPA,DHA and activityof SOD,and decrease in AA and MDA.Fish oil is a potential antisenilityagent. |
| Keywords: | fish oil eicosapentaenoic acid(EPA) docosahexaenoic acid(DHA) malondialdehyde(MDA) superoxide dismutase(SOD) |
| 本文献已被 CNKI 等数据库收录！ | |