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45例骨转移疼痛不同分割剂量放疗疗效分析
引用本文:梁晓东,陈卫军,贡强君,刘艳梅,应申鹏.45例骨转移疼痛不同分割剂量放疗疗效分析[J].肿瘤学杂志,2007,13(1):62-63.
作者姓名:梁晓东  陈卫军  贡强君  刘艳梅  应申鹏
作者单位:台州市中心医院,浙江,台州,318000
摘    要:目的]探讨不同分割剂量放疗对骨转移癌止痛的疗效。方法]45例骨转移癌病人采用三种不同分割剂量放疗,分别为DT40Gy/(20F·4w)、DT30Gy/(10F·2w)和DT20Gy/(5F·1w)。结果]患者止痛有效率为88.89%(40/45),其中25例获得完全缓解。DT40Gy/(20F·4w)组、DT30Gy/(10F·2w)组及DT20Gy/(5F·1w)组的CR率分别为63.64%、57.14%、33.33%;PR率分别为36.36%、32.14%和33.33%,差异均无显著性(P>0.05)。结论]不同分割剂量放疗对骨转移癌疼痛的缓解程度无影响。

关 键 词:骨肿瘤  肿瘤转移  疼痛  放射疗法  放射治疗剂量
文章编号:1671-170X(2007)01-0062-02
修稿时间:2006年12月4日

Radiotherapy with Different Fractionated Dose for 45 Cases with Malignant Bone Metastatic Pain
LIANG Xiao-dong,CHEN Wei-jun,GONG Qiang-Jun,et al..Radiotherapy with Different Fractionated Dose for 45 Cases with Malignant Bone Metastatic Pain[J].Journal of Oncology,2007,13(1):62-63.
Authors:LIANG Xiao-dong  CHEN Wei-jun  GONG Qiang-Jun  
Abstract:Purpose] To evaluate the effect of pain control with different fractionated dose of radiotherapy in bone metastases from malignancies. Methods] Forty-five cases with bone metastases received 3 fractionation schedules of radiotherapy: Group 1, 40Gy/20 fractions in 4 weeks; Group 2, 30Gy/10 fractions in 2 weeks and group 3, 20Gy/5 fractions in one week. Results] Overall pain relief rate was 88.89%(40/45), with complete relief (CR) in 25 cases. The CR rate in group 1,2 and 3 was 63.64%, 57.14%, 33.33% respectively; partial relief (PR) rate was 36.36%,32.14%,33.33% respectively, with no significant difference. Conclusion] Different fractionated dose of radiotherapy have no influence on pain relief in bone metastases.
Keywords:bone neoplasms  neoplasm metastases  pain  radiotherapy  radiotherapy dosage
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