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急性脑梗死患者血清sVAP-1的水平变化及临床意义
引用本文:徐玉龙,丁琪. 急性脑梗死患者血清sVAP-1的水平变化及临床意义[J]. 安徽医药, 2010, 14(5): 552-553. DOI: 10.3969/j.issn.1009-6469.2010.05.026
作者姓名:徐玉龙  丁琪
作者单位:安徽医科大学附属省立医院干部病房,安徽,合肥,230001;安徽医科大学附属省立医院干部病房,安徽,合肥,230001
摘    要:
目的观察急性脑梗死患者血清可溶性血管黏附蛋白-1(sVAP-1)的水平,探讨sVAP-1与急性脑梗死的关系及临床意义。方法随机选择急性脑梗死患者40例作为病例组,30例健康人为对照组,分别测定外周血清sVAP-1的水平。结果急性脑梗死组sVAP-1明显高于健康对照组(P〈0.05),且在脑梗死神经功能缺损程度重度组血清sVAP-1水平明显高于轻度组及中度组,差异有统计学意义(P〈0.05)。结论急性脑梗死患者血清sVAP-1水平升高,其水平增高可能会进一步加重脑梗死的发生与发展。

关 键 词:脑梗死  可溶性血管黏附蛋白-1

Clinical significance of serum soluble vascular adhesion protein-1 levels in acute cerebral infarction
XU Yu-long,DING Qi. Clinical significance of serum soluble vascular adhesion protein-1 levels in acute cerebral infarction[J]. Anhui Medical and Pharmaceutical Journal, 2010, 14(5): 552-553. DOI: 10.3969/j.issn.1009-6469.2010.05.026
Authors:XU Yu-long  DING Qi
Affiliation:XU Yu-long,DING Qi(Department of Cadre,AnHui Provincial Hospital,Hefei 230001,China)
Abstract:
Aim To observe serum soluble vascular adhesion protein-1(sVAP-1) levels of patients in acute cerebral infarction,to explore the sVAP-1 with acute cerebral infarction and its clinical significance.Methods 40 patients with acute cerebral infarction were randomly selected case group,30 healthy human as control group,and peripheral blood clearance sVAP-1 levels were measured.Results in acute cerebral infarction group sVAP-1 was significantly higher than the control group(P<0.05),and the extent of neurological deficits in cerebral infarction and severe serum sVAP-1 levels were significantly higher than the mild and moderate.The differences were statistically significant.Conclusion Patients of acute cerebral infarction have elevated levels of sVAP-1,whose increased levels may further increase the occurrence and development of cerebral infarction.
Keywords:cerebral infarction  soluble vascular adhesion protein-1
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