盐酸法舒地尔治疗脑梗塞64例临床疗效观察

目的 探讨盐酸法舒地尔治疗脑梗塞的临床疗效.方法 将我院2011年1月～ 2013年1月收治64例脑梗塞患者的随机分为观察组和对照组,每组各32例.观察组患者给予盐酸法舒地尔治疗；对照组患者给予川芎嗪治疗.采用神经功能缺损评分标准及日常生活活动能力（ADL）评分标准对临床疗效进行评价.结果 2组患者治疗后神经功能缺损及ADL评分均较治疗前有所改善,差异有统计学意义（P＜0.05）,观察组患者改善情况优于对照组患者,组间差异有统计学意义（P＜0.05）.结论 采用盐酸法舒地尔治疗脑梗塞的近期疗效显著,在改善脑梗塞患者神经功能和日常生活活动能力方面具有一定的优势,值得临床进一步推广使用.

Clinical observation of fasudil hydrochloride in treatment of 64 cases with cerebral infarction

Objective To explore the clinical effect of fasudil hydroehloride in treatment of cerebral infarction. Methods 64 cases of cerebral infarction in our hospital from January 2011 to January 2013 were randomly divided into an observation group and a control group,32 cases in each group. Cases in the observation group were treated with fasudil hydroehloride com- pared with those in the control group who were treated with ligustrazine. Standard score of neurological deficits and activities of daily living（ ADL） score were adopted to evaluate the clinical effect. Results The neurological impairment and ADL scores of all cases were improved after treatment. The difference was statistically significant （ P 〈 0.05 ）. Cases in the observation group were better improved than those in the control group. The difference between the two groups was significant（ P 〈 0.05）. Con- clusion Fasudil hydrochloride in treatment of cerebral infarction has good short-term efficacy, and has certain advantages in terms of improving neural function and activities of daily living. It is worth to be clinically applied.