Mitotic versus meiotic recombination in Saccharomyces cerevisiae

Summary As part of a comparative analysis of spontaneous mitotic and meiotic recombination we have compared the mitotic and meiotic maps of the wild type and yeast hybrids homozygous for reml-l, a mitosis-specific hyper-rec mutation (Golin and Esposito, 1977; Golin, 1979). In wild type yeast strains recombination in centromere proximal intervals occurs relatively more frequently in mitosis than in meiosis. In reml-1/rem1-1 hybrids the distribution of mitotic exchange events is more similar to the distribution observed in meiosis.