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Motor unit number index (MUNIX) in the orbicularis oculi muscle of healthy subjects
Authors:Suk‐Won Ahn MD  Ki‐Won Kim MT  Jee‐Eun Kim MD  PhD  Je‐Young Shin MD  Dong‐Gun Kim MD  Kwang‐Woo Lee MD  PhD  Jung‐Joon Sung MD  PhD
Affiliation:1. Department of Neurology, Chung‐Ang University Hospital, Chung‐Ang University College of Medicine, Seoul, Republic of Korea;2. Department of Neurology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea;3. Department of Neurology, Seoul Medical Center, Seoul, Republic of Korea
Abstract:
Introduction: The motor unit number index (MUNIX) refers to an electrophysiological method that measures the number of motor units in the surface electromyographic interference pattern (SIP) recorded during graded muscle contractions. MUNIX studies of limb muscles have been conducted, but MUNIX studies of bulbo‐facial muscles have not been reported. Methods: We assessed bilateral orbicularis oculi muscles using MUNIX, and the reference values and reproducibility of MUNIX and motor unit size index (MUSIX) were investigated in healthy subjects. Results: In this study, MUNIX was applied successfully to the orbicularis oculi muscles and showed good reproducibility. The correlation coefficients for MUNIX and MUSIX were 0.803 and 0.592, respectively, and the coefficients of variation were 20.9% and 8.5%, respectively. Conclusions: The MUNIX procedure for the orbicularis oculi muscle would be a useful tool for evaluating bulbar symptoms, especially in amyotrophic lateral sclerosis. Muscle Nerve 51 : 197–200, 2015
Keywords:amyotrophic lateral sclerosis  facial nerve  motor unit  MUNIX  orbicularis oculi muscle
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