| IMMUNOELECTRON MICROSCOPIC LOCALIZATION OF GROWTH FACTORS AND OTHER MARKERS IN HUMAN LONG－TERM BONE MARROW CULTURES |
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| 引用本文： | 刘杰文. IMMUNOELECTRON MICROSCOPIC LOCALIZATION OF GROWTH FACTORS AND OTHER MARKERS IN HUMAN LONG－TERM BONE MARROW CULTURES[J]. 中国医学科学杂志(英文版), 1996, 0(3) |
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| 作者姓名： | 刘杰文 |
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| 摘 要： | ＩＭＭＵＮＯＥＬＥＣＴＲＯＮＭＩＣＲＯＳＣＯＰＩＣＬＯＣＡＬＩＺＡＴＩＯＮＯＦＧＲＯＷＴＨＦＡＣＴＯＲＳＡＮＤＯＴＨＥＲＭＡＲＫＥＲＳＩＮＨＵＭＡＮＬＯＮＧ－ＴＥＲＭＢＯＮＥＭＡＲＲＯＷＣＵＬＴＵＲＥＳ￥ＬｉｕＪｉｅｗｅｎ;（刘杰文）,ＷｙｎｔｅｒＥ...
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IMMUNOELECTRON MICROSCOPIC LOCALIZATION OF GROWTH FACTORS AND OTHER MARKERS IN HUMAN LONG-TERM BONE MARROW CULTURES |
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| Liu Jiewen,Wynter E de,Testa NG,Dexter TM and Allen TD. IMMUNOELECTRON MICROSCOPIC LOCALIZATION OF GROWTH FACTORS AND OTHER MARKERS IN HUMAN LONG-TERM BONE MARROW CULTURES[J]. Chinese medical sciences journal, 1996, 0(3) |
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| Authors: | Liu Jiewen Wynter E de Testa NG Dexter TM Allen TD |
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| Abstract: | Ultrastructural immunocytochemical characterization of human long-term bone marrow cultures has shown positive localization for growth factors on cell surface and on extracellular matrix(ECM).In some cases double-labelling indicated co-localization of growth factors and specific cell surface labels.Specific markers for endothelial cells and fibroblasts showed that growth factor(GM-CSF,G-CSF and b-FGF) were present at the surface of these cell types.Both scanning and transmission electron microscopy indicated intense labelling for growth factors on the extracellular matrix.Double-labelling of heparan sulphate proteoglycans and GM-CSF showed a co-localization of the labelling,which indicated the binding of growth factor to the extracellular matrix. |
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| Keywords: | bone marrow growth factors specific markers |
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